發(fā)布時間：2018-06-19 00:57

  本文選題：中醫(yī)藥分步論治 + 腎虛肝郁血瘀　； 參考：《時珍國醫(yī)國藥》2017年11期

【摘要】：目的客觀分析中醫(yī)藥分步論治IVF-ET失敗患者再次IVF-ET降調(diào)日至胚胎移植日助孕療效。方法選取符合納入標(biāo)準(zhǔn)的137例四川大學(xué)華西第二醫(yī)院生殖中心行IVF-ET長方案失敗后的患者(腎虛肝郁血瘀型)為對象,采用隨機(jī)分組(治療組72例;對照組65例),觀察兩組治療后再次IVF-ET降調(diào)日至胚胎移植日助孕周期的獲成熟卵子數(shù)、受精卵數(shù)、受精率、獲新鮮胚胎數(shù)、HCG日及ET日子宮內(nèi)膜厚度、周期取消率、起始周期移植率、取卵周期移植率等情況。結(jié)果(1)中醫(yī)藥分步論治可改善IVF-ET患者的HCG日內(nèi)膜厚度、ET日內(nèi)膜厚度;提高獲受精卵數(shù)、受精率及獲新鮮胚胎數(shù)。治療前后比較:對照組差異無統(tǒng)計學(xué)意義(P0.05);治療組差異有統(tǒng)計學(xué)意義(P0.05),療后優(yōu)于療前。療后兩組組間比較,差異有統(tǒng)計學(xué)意義(P0.05),治療組優(yōu)于對照組。(2)中醫(yī)藥分步論治可提高IVF-ET患者的起始、取卵周期移植率,降低周期取消率。治療前后比較:治療組差異均有統(tǒng)計學(xué)意義(P0.05),療后優(yōu)于療前;對照組差異無統(tǒng)計學(xué)意義(P0.05)。療后兩組組間比較:采用χ2檢驗,差異均無統(tǒng)計學(xué)意義(P0.05)。結(jié)論中醫(yī)藥分步論治可改善IVF-ET患者的HCG日內(nèi)膜厚度、ET日內(nèi)膜厚度;提高獲受精卵數(shù)、受精率及獲新鮮胚胎數(shù);提高IVF-ET患者的起始、取卵周期移植率,降低周期取消率。
[Abstract]:Objective to analyze the therapeutic effect of IVF-ET on IVF-et failure from the day of lowering IVF-et to the day of embryo transfer. Methods 137 patients (kidney deficiency, liver stagnation and blood stasis) were selected from reproductive center of West China Hospital of Sichuan University after the failure of IVF-ET. The patients were randomly divided into two groups (treatment group, 72 cases). The number of mature eggs, fertilized eggs, fertilization rate, endometrial thickness on HCG day and et day, and the rate of cycle cancellation were observed in the control group (65 cases) from the second IVF-ET down-modulation day to the embryo transfer day, the number of fertilized eggs, the thickness of endometrium on the day of HCG and et, and the rate of cycle cancellation. The rate of initial cycle transplantation and oocyte cycle transplantation. Results 1) Chinese medicine can improve the thickness of HCG and et, increase the number of fertilized eggs, fertilization rate and the number of fresh embryos in IVF-ET patients. Comparison before and after treatment: there was no significant difference between control group (P 0.05) and treatment group (P 0.05), which was better than that before treatment. There was significant difference between the two groups after treatment. The treatment group was superior to the control group (P < 0.05). The treatment group was better than the control group. The step by step treatment with Chinese medicine could improve the initiation rate of IVF-ET patients, the transplant rate of oocyte collection cycle and the rate of cycle cancellation. Comparison before and after treatment: the difference between the treatment group and the control group was statistically significant (P 0.05), which was better than that before treatment, while in the control group there was no significant difference (P 0.05). After treatment, there was no significant difference between the two groups by 蠂 2 test (P 0.05). Conclusion Chinese medicine can improve the thickness of HCG and et in IVF-ET patients, increase the number of fertilized eggs, fertilization rate and the number of fresh embryos, increase the initiation of IVF-ET patients, the rate of oocyte cycle transplantation, and reduce the rate of cycle cancellation.
【作者單位】： 成都中醫(yī)藥大學(xué)附屬醫(yī)院;四川大學(xué)華西第二醫(yī)院;重慶市中醫(yī)院;成都西囡婦科醫(yī)院;成都中醫(yī)藥大學(xué)臨床醫(yī)學(xué)院;
【基金】：四川省科技廳科研項目(2016SZ0037) 四川省中醫(yī)藥管理局科研項目(2016C022)
【分類號】：R714.8

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本文編號：2037596