情感障礙與患者圍產(chǎn)期、胎兒期高危因素的相關(guān)性研究
本文選題:情感障礙 + 產(chǎn)科并發(fā)癥; 參考:《青島大學(xué)》2014年碩士論文
【摘要】:目的: 通過將情感障礙和非情感障礙患者接觸到胎兒期和圍產(chǎn)期高危因素進(jìn)行比較,探討情感障礙與患者胎兒期、圍產(chǎn)期高危因素的相關(guān)性。 方法: 回顧2012.09~2013.12在山東省青州榮軍醫(yī)院精神科住院的情感障礙患者,全部病例由本專業(yè)主治醫(yī)師以上資歷醫(yī)生給予明確診斷,診斷符合中國疾病分類方法與診斷標(biāo)準(zhǔn)第三版的修訂版情感性精神障礙的診斷標(biāo)準(zhǔn)(CCMD3)。將其與來自我院其他科室同期住院的非精神障礙患者進(jìn)行對照。由經(jīng)過專業(yè)培訓(xùn)的人員核對資料,并按統(tǒng)一標(biāo)準(zhǔn)整理后,采取雙人雙機(jī)錄入資料。使用Excel2003建立數(shù)據(jù)庫,采用SPSS17.0軟件進(jìn)行統(tǒng)計(jì)分析。以a=0.05為檢驗(yàn)水準(zhǔn)。對單因素分析中有統(tǒng)計(jì)學(xué)意義的危險(xiǎn)因素帶入Logistic回歸模型,用向后法逐步篩選變量。P0.05為有統(tǒng)計(jì)學(xué)意義。 結(jié)果: 兩組患者在母孕期精神狀況、母孕期接觸有毒物質(zhì)、母孕期感冒史、母孕期并發(fā)癥、母生產(chǎn)期并發(fā)癥、新生兒期并發(fā)癥、家族史等方面,差異有統(tǒng)計(jì)學(xué)意義(P0.05)。而母孕期感冒史、母生產(chǎn)期并發(fā)癥、陽性家族史是情感障礙患者患病的的高危因素(P0.05)。 討論: 本研究應(yīng)用了規(guī)范的病例對照研究方法,研究組與對照組在應(yīng)答率、性別、居住地、受教育程度、母孕年齡各因素?zé)o統(tǒng)計(jì)學(xué)差異(P0.05),說明病例組與對照組有很好的可比性。本研究顯示,母孕期感冒史、母生產(chǎn)期并發(fā)癥、陽性家族史是情感障礙患者患病的的高危因素。 結(jié)論 情感障礙患者組較對照組的產(chǎn)科并發(fā)癥的發(fā)生率高,情感障礙與患者圍產(chǎn)期、胎兒期高危因素有密切相關(guān)性,注重優(yōu)生優(yōu)育對控制情感障礙疾病的發(fā)生具有重要意義。
[Abstract]:Objective: to explore the relationship between affective disorder and perinatal risk factors by comparing the high risk factors of fetal and perinatal period in patients with affective disorder and non-affective disorder. Methods: the patients with affective disorder in Department of Psychiatry, Qingzhou Rongjun Hospital, Shandong Province, were retrospectively reviewed. The diagnostic criteria for affective disorders in accordance with the third edition of the Chinese Classification of Diseases and Diagnostic Standards are CCMD3. It was compared with non-mental disorder patients who were hospitalized in other departments of our hospital at the same time. By the professional training personnel check the data, and according to the unified standards, double-machine data entry. Using Excel 2003 to establish the database, SPSS 17.0 software for statistical analysis. Take A0. 05 as the test level. The risk factors with statistical significance in univariate analysis were brought into Logistic regression model, and the stepwise screening of variables (.P0.05) was statistically significant. Results: there were significant differences between the two groups in maternal mental status, maternal exposure to toxic substances, maternal cold history, maternal pregnancy complications, maternal birth complications, neonatal complications, family history and so on. Maternal cold history, maternal birth complications and positive family history were high risk factors for affective disorder patients (P 0.05). Discussion: the standard case-control study method was used in this study. The response rate, sex, place of residence, education level of the study group and the control group were studied. There was no significant difference in maternal pregnancy age between the two groups (P 0.05), which indicated that there was good comparability between the case group and the control group. This study showed that maternal pregnancy cold history, maternal birth complications, positive family history are high risk factors for affective disorder patients. Conclusion the incidence of obstetric complications in the affective disorder group is higher than that in the control group, and affective disorder is closely related to perinatal and fetal risk factors. It is of great significance to pay attention to eugenics and eugenics to control the occurrence of affective disorders.
【學(xué)位授予單位】:青島大學(xué)
【學(xué)位級別】:碩士
【學(xué)位授予年份】:2014
【分類號】:R714.2
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