本文選題：早孕期 + 孕酮��； 參考：《中國婦產(chǎn)科臨床雜志》2017年03期

【摘要】：目的比較正常妊娠結(jié)局和胚胎停育孕婦的早孕期孕酮水平,并隨訪早孕期孕激素補(bǔ)充治療的安全性。方法回顧性分析了2015年1月至2月在北京協(xié)和醫(yī)院分娩的144例孕婦的孕期資料,并與同期行孕酮檢測的53例胚胎停育患者的病例資料進(jìn)行比較,統(tǒng)計分析了早孕期孕酮的參考范圍及影響因素;對接受孕激素治療患者試圖評估其安全性。結(jié)果正常妊娠人群的早孕期孕酮正常低限為11 ng/ml,孕酮水平與患者的年齡、甲狀腺功能、是否合并糖尿病、是否有先兆流產(chǎn)癥狀、孕周并未發(fā)現(xiàn)相關(guān)性。胚胎停育患者孕酮水平與正常妊娠孕婦無顯著差別,但發(fā)生胚胎停育近期監(jiān)測的孕酮水平可有明顯下降。使用孕激素治療可能與胎盤粘連有關(guān)。結(jié)論亟需建立早孕期孕酮的正常參考范圍以規(guī)范對孕酮水平的解釋;需關(guān)注孕激素補(bǔ)充治療與胎盤粘連的相關(guān)性。
[Abstract]:Objective to compare the levels of progesterone in early pregnancy with normal pregnancy outcome and embryo arrest, and to follow up the safety of progesterone supplementation in early pregnancy. Methods the pregnant data of 144 pregnant women who gave birth in Beijing Union Hospital from January to February 2015 were analyzed retrospectively, and the data of 53 cases of aborted embryo with progesterone were compared. The reference range and influencing factors of progesterone in early pregnancy were statistically analyzed, and the safety of progesterone was evaluated in patients treated with progesterone. Results the normal limit of progesterone in early pregnancy was 11 ng / ml. There was no correlation between progesterone level and age, thyroid function, diabetes mellitus, threatened abortion, gestational week. There was no significant difference in progesterone level between normal pregnant women and normal pregnant women, but the progesterone level monitored in the near term was significantly decreased. Progesterone therapy may be associated with placental adhesion. Conclusion it is urgent to establish the normal reference range of progesterone in early pregnancy in order to standardize the explanation of progesterone level and to pay attention to the correlation between progesterone supplementation therapy and placental adhesion.
【作者單位】： 中國醫(yī)學(xué)科學(xué)院北京協(xié)和醫(yī)院婦產(chǎn)科;
【分類號】：R714.2

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