本文選題：妊娠期糖尿病 + 甘露糖結(jié)合凝集素�。� 參考：《實(shí)用醫(yī)學(xué)雜志》2015年20期

【摘要】：目的:探討妊娠期糖尿病(GDM)孕婦血漿甘露糖結(jié)合凝集素(MBL)及內(nèi)毒素(LPS)水平變化及其與體質(zhì)指數(shù)(BMI)的關(guān)系。方法:納入新診斷的GDM組孕婦及正常組孕婦各45例,測(cè)定血漿MBL、LPS濃度;每組按BMI(25 kg/m2)為界分為肥胖亞組(BMI≥25 kg/m2)和非肥胖亞組(BMI25 kg/m2),分析GDM組孕婦血漿MBL、LPS水平變化及其與BMI的相關(guān)性。結(jié)果 :GDM組MBL濃度低于正常組,而LPS濃度明顯高于正常組,差異具有統(tǒng)計(jì)學(xué)意義(P0.05);Pearson相關(guān)性分析顯示GDM孕婦血漿BMI與MBL呈負(fù)相關(guān)(r=-0.28,P0.05),BMI與LPS呈明顯正相關(guān)(r=0.62,P0.05);LPS與MBL呈負(fù)相關(guān)(r=-0.43,P0.05)。正常組MBL、LPS與BMI之間的這種相關(guān)性不存在。結(jié)論 :MBL和LPS可能是超重孕婦GDM發(fā)病的兩個(gè)重要危險(xiǎn)因素,對(duì)臨床GDM防治可能具有重要意義。
[Abstract]:Objective: to investigate the changes of plasma mannose binding lectin (MBL) and endotoxin (LPS) levels in pregnant women with gestational diabetes mellitus (GDM) and the relationship between plasma mannose binding lectin (MBL) and body mass index (BMI). Methods: the plasma concentration of GDM was measured in 45 pregnant women in the newly diagnosed group and 45 pregnant women in the normal group. Each group was divided into obese subgroup (BMI 鈮，

本文編號(hào)：1960475