婦科腫瘤患者醫(yī)院感染特征及相關(guān)易感因素分析
發(fā)布時間:2018-05-30 16:52
本文選題:婦科腫瘤 + 感染; 參考:《中國病原生物學(xué)雜志》2017年09期
【摘要】:目的分析婦科腫瘤患者醫(yī)院感染特征及相關(guān)易感因素,為臨床感染防控提供指導(dǎo)。方法收集564例婦科腫瘤患者臨床資料,采用全自動細菌微生物鑒定儀鑒定病原菌。采用K-B紙片擴散法檢測病原菌的耐藥情況,分析患者感染的易感因素。結(jié)果 564份婦科腫瘤患者各類送檢標(biāo)本中分離出病原菌170株(30.14%);181份生殖道標(biāo)本分離出93株,164份泌尿道標(biāo)本分離出41株,117份呼吸道標(biāo)本分離出25株,102份口腔標(biāo)本分離出11株,分離率分別為51.38%、25.00%、21.37%和10.78%;170株病原菌中革蘭陰性菌105株,革蘭陽性菌50株,真菌15株。革蘭陰性菌中大腸埃希菌53株,肺炎克雷伯菌24株,其他革蘭陰性菌28株;革蘭陽性菌中表皮葡萄球菌21株,金黃色葡萄球菌14株,其他革蘭陽性菌15株;真菌中白色假絲酵母菌11株,近平滑假絲酵母菌4株。大腸埃希菌對頭孢唑啉、環(huán)丙沙星、慶大霉素、萬古霉素、美羅培南的耐藥率分別為100.00%、7.55%、52.83%、0.00%和0.00%;表皮葡萄球菌對頭孢唑啉、環(huán)丙沙星、慶大霉素、萬古霉素、美羅培南的耐藥率分別為28.57%、76.19%、52.38%、0.00%和23.81%。年齡≥60歲、接受化療、合并慢性疾病、使用抗菌藥物、住院時間≥1個月均為婦科腫瘤患者醫(yī)院感染易感因素。結(jié)論婦科腫瘤患者感染病原菌類型以大腸埃希菌和表皮葡萄球菌為主,生殖道是病原菌主要感染部位。大腸埃希菌感染可選用美羅培南,表皮葡萄球菌感染可選用萬古霉素進行治療。
[Abstract]:Objective to analyze the characteristics of nosocomial infection and related susceptible factors in gynecological tumor patients, and to provide guidance for clinical infection prevention and control. Methods the clinical data of 564 patients with gynecological tumors were collected. K-B disk diffusion method was used to detect the drug resistance of pathogenic bacteria and the susceptible factors of infection were analyzed. Results 170 strains of pathogenic bacteria were isolated from 181 genitourinary tract specimens of 564 gynecological tumor patients, and 93 strains of urethra were isolated from 164 specimens of urinary tract, 41 strains from 117 respiratory tract specimens, 25 strains from 102 oral specimens, and 11 strains from oral cavity. The isolation rates were 21.37% and 10.78%, respectively, of which 105 were gram-negative bacteria, 50 Gram-positive bacteria and 15 fungi. Among them, 53 were Escherichia coli, 24 were Klebsiella pneumoniae, 28 were other gram-negative bacteria, 21 were Staphylococcus epidermidis, 14 were Staphylococcus aureus, and 15 were Gram-positive bacteria. There were 11 strains of Candida albicans and 4 strains of Candida albicans. The resistance rates of Escherichia coli to cefazolin, ciprofloxacin, gentamicin, vancomycin and meropenem were 100.007.5552.83% and 0.00000%, respectively, while Staphylococcus epidermidis was resistant to cefazolin, ciprofloxacin, gentamycin, vancomycin, and vancomycin. The drug resistance rate of meropenem was 28.57 and 76.19%, respectively, and that of meropenem was 0.00% and 23.81%, respectively. The risk factors of nosocomial infection in gynecological tumor patients were the age 鈮,
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