本文選題：促性腺素類 + 分裂期��； 參考：《重慶醫(yī)學(xué)》2017年15期

【摘要】：目的探討行選擇性單胚胎移植(eSET)的臨床結(jié)局及可行性。方法回顧性分析2014年8月至2015年10月在該院生殖科進(jìn)行體外受精-胚胎移植(IVF-ET)治療的患者資料,選擇行選擇性移植1枚優(yōu)質(zhì)胚胎106個(gè)周期為eSET組,其中獲卵數(shù)大于15個(gè)為高反應(yīng)組(高度OHSS風(fēng)險(xiǎn),46個(gè)周期),獲卵數(shù)5~15個(gè)為正常反應(yīng)組(60個(gè)周期)。移植2枚胚胎(至少1枚為優(yōu)質(zhì)胚胎)的106個(gè)周期為雙胚胎移植組(DET)組。比較組間一般情況、促排情況、胚胎發(fā)育情況及臨床妊娠率、種植率、多胎率和早期流產(chǎn)率。結(jié)果 eSET組Gn量和雙胎妊娠率低于DET組,注射人絨毛膜促性腺激素(HCG)日雌激素(E_2)水平、獲卵數(shù)、優(yōu)質(zhì)胚胎數(shù)和種植率均高于DET組,比較差異有統(tǒng)計(jì)學(xué)意義(P0.05)。高反應(yīng)組注射HCG日E_2水平高于正常反應(yīng)組,比較差異有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論 eSET與DET有相似的妊娠率,但能明顯降低雙胎妊娠率,對(duì)于特定人群應(yīng)該堅(jiān)持行eSET。
[Abstract]:Objective to investigate the clinical outcome and feasibility of selective single embryo transfer (eSET). Methods a retrospective analysis was made of the patients' data from August 2014 to October 2015 in the Department of reproductive department for the treatment of in vitro fertilization and embryo transfer (IVF-ET). Selective transplantation of 1 high quality embryos in 106 cycles was selected as eSET group, and the number of acquired eggs was higher than that of 15. The group (high OHSS risk, 46 cycles) and the number of acquired eggs were 5~15 as the normal reaction group (60 cycles). The 106 cycles of the transplantation of 2 embryos (at least 1 for high quality embryos) were in the double embryo transfer group (DET) group. The general situation, the condition of promoting, the embryo development and the clinical pregnancy rate, the implantation rate, the rate of multifoetus and the early abortion rate were compared, and the result was eSET. The rate of Gn and twin pregnancy was lower than that in group DET. The level of estrogen (E_2), the number of eggs obtained, the number of high quality embryos and the planting rate were higher than those in the DET group, and the difference was statistically significant (P0.05). The level of E_2 in the high reaction group was higher than that in the normal reaction group (P0.05). The difference was statistically significant (P0.05). Conclusion eSET and conclusion were statistically significant (P0.05). Conclusion eSET and conclusion were statistically significant (P0.05). Conclusion eSET and conclusion are statistically significant (P0.05). Conclusion eSET and conclusion are statistically significant (P0.05). Conclusion eSET and conclusion are statistically significant (P0.05). Conclusion eSET and conclusion are statistically significant (P0.05). Conclusion eSET and conclusion are statistically significant (P0.05). Conclusion eSET and HCG DET has similar pregnancy rate, but it can significantly reduce the rate of twin pregnancy. For specific populations, eSET. should be maintained.
【作者單位】： 海南省農(nóng)墾總醫(yī)院生殖科;
【基金】：海南省衛(wèi)生廳課題(瓊衛(wèi)2013自籌-20)
【分類號(hào)】：R714.8

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