本文選題：妊娠期糖尿病 + 發(fā)病率�。� 參考：《南京醫(yī)科大學(xué)學(xué)報(bào)(自然科學(xué)版)》2015年05期

【摘要】：目的 :分析孕婦妊娠期糖尿病(gestational diabetes mellitus,GDM)發(fā)病情況及危險(xiǎn)因素。方法 :收集2012年1月1日~2013年12月31日本院產(chǎn)科門診隨診并住院分娩的孕婦資料2 748例,通過(guò)口服75 g葡萄糖耐量試驗(yàn)(OGTT)篩查GDM,評(píng)估發(fā)病率、相關(guān)危險(xiǎn)因素。結(jié)果:12 748例孕婦中GDM 540例,非GDM 2 208例,GDM發(fā)病率19.65%;2GDM組年齡、孕前BMI、產(chǎn)前BMI、孕期體重增加值、新生兒體重較非GDM組均有升高(P0.05);3單因素分析顯示年齡(≥30歲)(OR=1.868,P0.001)、自然流產(chǎn)史(OR=1.673,P0.001)、高血壓病史(OR=2.509,P=0.017)、糖尿病家族史(OR=5.776,P0.001)、孕前BMI≥24(OR=2.981,P0.001)、孕期體重增長(zhǎng)情況(OR=1.923,P0.001)均是GDM發(fā)生的相關(guān)危險(xiǎn)因素。進(jìn)一步行多因素Logistic回歸顯示年齡≥30歲(OR=1.406,P=0.006)、自然流產(chǎn)史(OR=1.462,P=0.003)、糖尿病家族史(OR=4.969,P0.001)、孕前BMI≥24(OR=1.475,P=0.035)、孕期體重增長(zhǎng)幅度≥16.0 kg(OR=1.846,P0.001)與GDM發(fā)生有關(guān);而妊娠期貧血孕婦GDM的發(fā)生率為無(wú)貧血孕婦的0.518倍(OR=0.518,P0.001);4無(wú)高危因素組GDM發(fā)病率11.95%,當(dāng)高危因素≥4個(gè),GDM發(fā)病率達(dá)65.00%(χ2=144.182,P0.001)。結(jié)論:孕前BMI≥24、年齡≥30歲、自然流產(chǎn)病史、DM家族史、孕期體重增加≥16 kg等因素為GDM發(fā)生的獨(dú)立危險(xiǎn)因素,妊娠期貧血可降低GDM發(fā)生。加強(qiáng)孕前、孕期高危因素篩查、干預(yù),有利于減少GDM發(fā)生。
[Abstract]:Objective: to analyze the incidence and risk factors of gestational diabetes mellitusus (GDM) in pregnant women with gestational diabetes mellitus (GDM). Methods: from January 1, 2012 to December 31, 2013, 2 748 pregnant women who were followed up and delivered in hospital were collected. GDMs were screened by oral glucose tolerance test (OGTT), and the incidence and risk factors were evaluated. Results among 12 748 pregnant women, 540 cases were GDM, and 19.65 cases were non-GDM cases. The age, pre-pregnancy, prenatal GDM, weight gain during pregnancy were 19.65% and 19.65%, respectively. The univariate analysis showed that the age (鈮，

本文編號(hào)：1926514