本文選題：宮頸腫瘤 + 彌散加權成像　； 參考：《腫瘤》2015年06期

【摘要】：目的 :探討彌散加權成像(dif usion-weighted imaging,DWI)聯(lián)合常規(guī)磁共振成像(magnetic resonance imaging,MRI)檢查對宮頸癌診斷分期及治療方式選擇的價值。方法 :回顧性分析42例經(jīng)病理學證實的宮頸癌患者的DWI MRI資料,分析不同病理類型和病理分期宮頸癌的表觀彌散系數(shù)(apparent dif usion coef cient,ADC)和指數(shù)化表觀彌散系數(shù)(exponential apparent dif usion coef cient,e ADC),并與正常宮頸的ADC和e ADC以及術后病理分期結果進行比較。對放化療組和手術組患者治療前的ADC和e ADC進行比較。結果 :宮頸癌在DWI上呈現(xiàn)高信號,而正常宮頸無明顯異常信號。42例宮頸癌患者宮頸癌組織的平均ADC小于18例正常宮頸組織(P=0.000);宮頸鱗癌組織的平均ADC小于腺癌組織(P=0.036);放化療組治療前宮頸癌組織的平均ADC明顯小于手術組(P=0.000),而e ADC明顯大于手術組(P=0.000)。不同病理分期宮頸癌組織的平均ADC和e ADC的差異均有統(tǒng)計學意義(P值均0.05)。常規(guī)MRI和DWI聯(lián)合MRI對宮頸癌分期診斷的準確率分別為92.9%(39/42)和95.2%(40/42)(Kappa值分別為0.903 5和0.935 8,P0.01)。結論 :DWI聯(lián)合MRI在宮頸癌的診斷分期中具有較高的應用價值,ⅡB期宮頸癌的ADC可作為治療方式選擇的參考依據(jù)。
[Abstract]:Objective: to evaluate the value of diffusion-weighted imaging (DWI) combined with conventional magnetic resonance imaging (MRI) in the diagnosis, staging and treatment of cervical cancer. Methods: the DWI MRI data of 42 patients with cervical cancer confirmed by pathology were analyzed retrospectively. The apparent diffusion coefficient (dif usion coef) and exponential apparent dif usion coef diffusion coefficient (ADCA) of cervical carcinoma with different pathological types and stages were analyzed and compared with ADC and e ADC of normal cervix and postoperative pathological staging. ADC and e ADC were compared before treatment between radiotherapy and chemotherapy group and operation group. Results: cervical cancer showed high signal intensity on DWI. There was no obvious abnormal signal in normal cervix. The average ADC of cervical cancer in 42 cases of cervical cancer was less than that of 18 cases of normal cervical tissue, the average ADC of squamous cell carcinoma of cervix was lower than that of adenocarcinoma of cervix. The average ADC of cervical carcinoma before radiotherapy and chemotherapy was lower than that of carcinoma of cervix. The mean ADC was significantly lower than that of the operation group (P < 0. 000), and the e ADC was significantly higher than that of the operation group (P < 0. 000). There were significant differences in average ADC and e ADC in cervical carcinoma with different pathological stages (P = 0.05). The accuracy of conventional MRI and DWI combined with MRI in the diagnosis of cervical carcinoma staging was 92.939 / 42) and 95.2%(40/42)(Kappa value was 0.903 5 and 0.935 8g / P 0.01, respectively. Conclusion MRI combined with DWI has a high value in the diagnosis and staging of cervical cancer. The ADC of stage 鈪，

本文編號：1891047