本文選題：子宮內(nèi)膜異位癥(EMS) + 縮宮素受體(OTR)�。� 參考：《中華生殖與避孕雜志》2017年03期

【摘要】：目的探討縮宮素受體(OTR)在子宮內(nèi)膜異位癥(EMS)子宮結(jié)合帶中的表達水平及臨床意義。方法收集因EMS行子宮切除術(shù)的子宮結(jié)合帶蠟塊組織43例為EMS組,其中增生期25例,分泌期18例。收集同期因?qū)m頸癌、卵巢癌或?qū)m頸上皮內(nèi)瘤變Ⅲ級行子宮切除術(shù)的患者子宮結(jié)合帶蠟塊組織54例為對照組,其中增生期28例,分泌期26例。采用免疫組織化學方法檢測各組子宮結(jié)合帶組織中OTR的表達水平。結(jié)果對照組增生期子宮結(jié)合帶OTR(0.156±0.056)表達高于分泌期子宮結(jié)合帶OTR(0.126±0.030),差異有統(tǒng)計學意義(P=0.017)。EMS組增生期(0.205±0.106)和分泌期(0.187±0.070)子宮結(jié)合帶OTR含量表達無統(tǒng)計學差異(P=0.523),且含量分別高于對照組(0.156±0.056,0.126±0.030)相應(yīng)月經(jīng)周期子宮結(jié)合帶OTR的表達,差異均有統(tǒng)計學意義(P=0.043,P=0.002)。EMS組子宮結(jié)合帶中OTR的表達水平與痛經(jīng)程度呈正相關(guān)(r=0.836,P0.05)。結(jié)論 EMS子宮結(jié)合帶縮宮素受體異常高表達,表明其可能和EMS的發(fā)病及引起的相關(guān)癥狀有關(guān)。
[Abstract]:Objective to investigate the expression and clinical significance of oxytocin receptor (OTRR) in uterine binding zone of endometriosis. Methods 43 cases of uterine binding paraffin tissue underwent hysterectomy with EMS were divided into EMS group (25 cases in proliferative phase and 18 cases in secretory phase). Fifty-four cases of uterine binding waxed tissue were collected as control group, 28 cases in proliferative phase and 26 cases in secretory phase. The patients with cervical cancer, ovarian cancer or cervical intraepithelial neoplasia grade 鈪，

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