本文選題：妊娠晚期 + B族鏈球菌　； 參考：《檢驗醫(yī)學》2016年04期

【摘要】：目的建立產(chǎn)前篩查B族鏈球菌(GBS)檢驗方法,將其應用于孕晚期GBS攜帶的篩查,探討妊娠晚期對孕婦進行GBS感染篩查的臨床意義,并對GBS帶菌者采取干預措施,觀察其對母嬰感染的防控作用。方法選取產(chǎn)科進行產(chǎn)前檢查及分娩的35周以上的孕婦1 000例為研究對象,采集孕婦陰道口1/3處及肛周分泌物進行GBS篩查,采用已建立的細菌培養(yǎng)法檢測GBS,將GBS陽性者根據(jù)其意愿分為干預治療組和不干預治療組,干預治療組在臨產(chǎn)后或破膜后預防性應用抗菌藥物,不干預治療組不作處理。對比各組產(chǎn)婦的妊娠結局。結果 1 000例受檢孕婦經(jīng)檢測共發(fā)生GBS感染97例,感染率為9.7%;與GBS陰性組相比,干預治療組胎膜早破、早產(chǎn)、宮內(nèi)感染、胎兒窘迫、新生兒低體質量、Apgar評分及感染發(fā)生率差異均無統(tǒng)計學意義(P0.05);而與不干預治療組相比,干預治療組Apgar評分差異無統(tǒng)計學意義(P0.05),其他指標差異均有統(tǒng)計學意義(P0.05)。結論建立的篩查GBS方法可快速、敏感、特異地篩查出孕婦陰道及肛周樣本中的GBS。孕晚期對孕婦進行GBS感染的篩查非常重要,及時采取干預措施可有效減少不良妊娠結局及母嬰感染的發(fā)生率。
[Abstract]:Objective to establish a prenatal screening method for B Streptococcus (GBS), and to apply it to the screening of GBS in the late pregnancy, to explore the clinical significance of GBS infection screening for pregnant women in the late pregnancy, and to take intervention measures for the GBS carriers to observe the prevention and control of maternal and infant infection. The method of obstetrics was selected for prenatal examination and more than 35 weeks of childbirth. 1000 cases of pregnant women were studied. GBS screening of 1/3 and perianal secretion of pregnant women was collected. The established bacterial culture method was used to detect GBS. The GBS positive people were divided into the intervention treatment group and the non intervention group according to their wishes. The intervention treatment group was used to prevent the antibiotics after the delivery or after the rupture of the membrane. No intervention treatment group was not used. Results 1000 cases of pregnant women received GBS infection in 97 cases, the infection rate was 9.7%, compared with the GBS negative group, the intervention group had no significant difference between the premature rupture of the membranes, the premature birth, the intrauterine infection, the fetal distress, the low body mass of the newborn, the Apgar score and the incidence of infection. There was no significant difference in Apgar score in intervention treatment group (P0.05), and there were significant differences in other indicators (P0.05). Conclusion the established screening GBS method can be quickly, sensitive and specific screening of pregnant women in the vaginal and anal weeks of pregnant women in the late GBS. pregnancy screening for pregnant women to carry out GBS infection screening is very important, timely take dry. Pre measures can effectively reduce adverse pregnancy outcomes and the incidence of maternal and infant infections.

【作者單位】： 金華市人民醫(yī)院;金華市婺城區(qū)婦幼保健院;金華市職業(yè)技術學院;
【基金】：2014年金華市科技計劃項目(2014-3-067)
【分類號】：R714.251;R446.5

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