補(bǔ)腎健脾方聯(lián)合西藥治療妊娠早期脾腎兩虛型先兆流產(chǎn)的臨床研究
本文選題:脾腎兩虛 + 先兆流產(chǎn)。 參考:《北京中醫(yī)藥大學(xué)》2015年碩士論文
【摘要】:概述:先兆流產(chǎn)(threatened abortion)是目前臨床上較常見(jiàn)的一種妊娠早期疾病之一其臨床表現(xiàn)為妊娠早期陰道出血、小腹墜痛、腰酸等。研究目的:本論文通過(guò)對(duì)先兆流產(chǎn)的中西醫(yī)治療現(xiàn)狀的概述及相關(guān)臨床病例的研究,探討以中西醫(yī)結(jié)合的方式來(lái)治療妊娠早期脾腎兩虛型先兆流產(chǎn),對(duì)其進(jìn)行臨床癥狀改善程度的評(píng)價(jià),對(duì)其3項(xiàng)血清指標(biāo)進(jìn)行對(duì)比總結(jié)。方法:對(duì)符合妊娠早期脾腎兩虛型先兆流產(chǎn)診斷標(biāo)準(zhǔn)的100例患者,隨機(jī)分為試驗(yàn)組與對(duì)照組兩組,試驗(yàn)組患者口服自擬方補(bǔ)腎健脾方并同時(shí)肌肉注射黃體酮注射液和口服地區(qū)孕酮片;對(duì)照組患者僅肌肉注射黃體酮注射液及口服地屈孕酮片;分別觀察并記錄治療各周后其3項(xiàng)指標(biāo)的檢查結(jié)果,討論其結(jié)果對(duì)兩組患者的總體療效及中醫(yī)癥候?qū)W療效進(jìn)行分析。研究結(jié)果:試驗(yàn)組總有效率98.00%,痊愈4例(8.00%),顯效25例(50.00%),有效20例(40.00%),無(wú)效1例(2.00%)。對(duì)照組50例患者,治療成功42例,8例治療期間胚胎停育。對(duì)照組總有效率84.00%,痊愈2例(4.00%),顯效15例(30.00%),有效25例(50.00%),無(wú)效8例(16.00%)。中西藥聯(lián)合用藥治療組臨床療效明顯優(yōu)于單純西藥治療組(P0.05)。中西藥聯(lián)合治療組接受治療后的3項(xiàng)觀察指標(biāo)血清孕酮(P)、血清雌二醇(E2)、人絨毛膜促性腺激素(HCG),較治療前均有明顯的變化。研究結(jié)論:采用中西藥結(jié)合治療妊娠早期脾腎兩虛型先兆流產(chǎn)較單純西藥治療效果要好;使用補(bǔ)腎健脾方辨治先兆流產(chǎn)對(duì)早孕期間臨床癥狀的緩解有較明顯的效果;同時(shí)能較明顯的提高先兆流產(chǎn)患者的各項(xiàng)激素水平,從臨床癥狀方面及實(shí)驗(yàn)室檢驗(yàn)結(jié)果方面均有較明顯的療效。
[Abstract]:Summary: threatened abortion is one of the most common diseases in early pregnancy. Objective: to explore the treatment of threatened abortion with the combination of traditional Chinese and western medicine in early pregnancy by summarizing the current situation of TCM and western medicine treatment of threatened abortion and the study of related clinical cases in order to explore the treatment of threatened abortion with deficiency of both spleen and kidney in early pregnancy. The degree of improvement of clinical symptoms was evaluated and three serum indexes were compared and summarized. Methods: 100 cases of threatened abortion with deficiency of spleen and kidney in early pregnancy were randomly divided into two groups: experimental group and control group. The patients in the test group were treated by oral administration of Bushen Jianpi recipe, intramuscular injection of progesterone and oral progesterone tablets, while patients in the control group were only given intramuscular injection of progesterone and oral diproprogesterone. The results of three indexes were observed and recorded respectively after treatment for each week, and the results were discussed for the analysis of the overall curative effect of the two groups and the curative effect of TCM syndromes. Results: in the test group, the total effective rate was 98.00. The total effective rate was 8.00%, the remarkable effect was 50.00000 in 25 cases, the effective rate was 40.00000 in 20 cases, and 2.00% was ineffective in 1 case. In the control group of 50 cases, 42 cases were successfully treated and 8 cases were aborted during the treatment. In the control group, the total effective rate was 84.00%, 2 cases were cured and 4.00%, 15 cases were significantly effective, 25 cases were effective and 50.00,8 cases were ineffective. The clinical effect of combined Chinese and western medicine treatment group was better than that of pure western medicine treatment group (P 0.05). There were significant changes in serum progesterone, estradiol E _ 2 and HCG in the treatment group after treatment. Conclusion: the combination of traditional Chinese medicine and western medicine in the treatment of threatened abortion with deficiency of both spleen and kidney in early pregnancy is better than that of western medicine alone, and the treatment of threatened abortion with Bushen Jianpi recipe has obvious effect on the relief of clinical symptoms during early pregnancy. At the same time, it can obviously improve the hormone level of threatened abortion patients, and has obvious curative effect from clinical symptoms and laboratory test results.
【學(xué)位授予單位】:北京中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】:碩士
【學(xué)位授予年份】:2015
【分類號(hào)】:R714.21
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