本文選題：慢性子宮內(nèi)膜炎 + CD　； 參考：《中山大學(xué)學(xué)報(bào)(醫(yī)學(xué)科學(xué)版)》2015年04期

【摘要】：【目的】探討CD138免疫組化在慢性子宮內(nèi)膜炎(CE)診斷中的作用,及助孕患者合并CE的高危因素。【方法】選取93例檢查證實(shí)為正常宮腔形態(tài),準(zhǔn)備行助孕治療的患者為研究對(duì)象,取子宮內(nèi)膜組織進(jìn)行常規(guī)HE染色和CD138免疫組化染色,同時(shí)收集患者病史、跟蹤其生殖預(yù)后�！窘Y(jié)果】1CE的檢出率:CD138免疫組化高于HE染色(27.96%vs 26.89%,P0.05);2妊娠率:CD138陽性患者(7.7%)比CD138陰性患者(31.3%)低(P=0.017);3單因素分析結(jié)果表明既往有月經(jīng)淋漓不盡史、人流史及合并有輸卵管堵塞等與CE有一定聯(lián)系(P0.05),Logistic回歸分析結(jié)果證實(shí)月經(jīng)淋漓不盡(P=0.014,OR=5.394,95%CI1.405-20.699),既往人流史(P=0.029,OR=3.194,95%CI1.125-9.073)、輸卵管堵塞(P=0.028,OR=3.274,95%CI1.139-9.415)是CD138陽性的獨(dú)立危險(xiǎn)因素�！窘Y(jié)論】CD138免疫組化可提高CE診斷率,既往淋漓不盡病史、人流史輸卵管堵塞病史是慢性子宮內(nèi)膜炎的高危因素,應(yīng)建議其進(jìn)行CD138免疫組化檢測(cè)。
[Abstract]:[objective] to investigate the role of CD138 immunohistochemistry in the diagnosis of chronic endometritis and the high risk factors of CE in pregnant patients. Endometrial tissues were collected for routine HE staining and CD138 immunohistochemical staining. [results] the positive rate of 1CE was 27.96% higher than that of HE staining (27.96 vs 26.89%). The pregnancy rate of patients with positive CD138 CD138 was lower than that of patients with negative CD138. The results of univariate analysis showed that there was no history of menstruation. Logistic regression analysis showed that the history of abortion and the combination of tubal blockage and CE were independent risk factors of CD138 positive. [conclusion] CD138 immunohistochemistry can improve the diagnostic rate of CD138. [conclusion] Immunohistochemistry of CD138 can improve the diagnostic rate of CE. The history of tubal obstruction is a high risk factor for chronic endometritis. It should be suggested that CD138 immunohistochemistry should be performed.
【作者單位】： 中山大學(xué)附屬第一醫(yī)院婦產(chǎn)科;中山大學(xué)附屬第一醫(yī)院病案管理科;中山大學(xué)附屬第一醫(yī)院病理科;
【基金】：廣東省科技計(jì)劃項(xiàng)目(2013B021800237、2012B040304007) 廣州市科技計(jì)劃項(xiàng)目(201300000169)
【分類號(hào)】：R711.74

【共引文獻(xiàn)】

相關(guān)期刊論文 前3條

1 馮衛(wèi)彤;王歡華;古衍;;不明原因早期復(fù)發(fā)性流產(chǎn)患者的宮腔鏡檢查[J];分子影像學(xué)雜志;2015年03期

2 馮燕，

本文編號(hào)：1876431