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羊膜聯(lián)合大黃、芒硝促進(jìn)切口愈合的臨床研究

發(fā)布時間:2018-05-11 18:31

  本文選題:羊膜 + 大黃; 參考:《新鄉(xiāng)醫(yī)學(xué)院》2014年碩士論文


【摘要】:背景:近年來如何做到術(shù)后減輕疼痛甚至無瘢痕愈合愈來愈受婦產(chǎn)科醫(yī)生的重視。中藥成分紫河車主要來自胎盤中的胎膜,在促進(jìn)上皮干細(xì)胞及毛細(xì)血管再生、減少瘢痕中重要成分纖維化因子形成等各方面有重要作用。大黃配伍芒硝在促進(jìn)剖宮產(chǎn)皮膚切口愈合中的作用已被認(rèn)可,能促進(jìn)切口愈合。羊膜與大黃、芒硝兩者聯(lián)合在切口愈合中的應(yīng)用目前在國內(nèi)外鮮見報道,本研究將探討羊膜聯(lián)合大黃、芒硝促進(jìn)剖宮產(chǎn)皮膚切口愈合的重要療效。 目的:研究剖宮產(chǎn)皮膚切口不同處理方法,利用術(shù)后切口疼痛、腫脹程度,瘢痕形成程度、切口愈合等級綜合判斷剖宮產(chǎn)切口愈合情況,探討羊膜聯(lián)合大黃、芒硝促進(jìn)剖宮產(chǎn)切口愈合的療效 方法:選擇2011年1月-2012年10月在濮陽市油田總醫(yī)院產(chǎn)科行擇期剖宮產(chǎn)分娩的健康產(chǎn)婦共400人,隨機分為4組,每組100人。所有病人皮膚切口僅縫合皮下組織,不縫合皮膚。研究1組術(shù)畢切口外敷自體羊膜,術(shù)后1天聯(lián)合大黃、芒硝外敷切口直至術(shù)后5天;研究2組術(shù)畢皮膚切口外敷自體羊膜,術(shù)后常規(guī)換藥;研究3組術(shù)畢皮膚切口常規(guī)包扎,術(shù)后1天切口外敷大黃、芒硝直至術(shù)后5天;對照4組術(shù)畢皮膚切口常規(guī)包扎,術(shù)后常規(guī)換藥。 結(jié)果: 1.研究1組、2組、3組與對照4組相比,術(shù)后瘢痕形成顯著者所占比例明顯降低,但只有研究1組與對照組差異有統(tǒng)計學(xué)意義(P0.05);研究1組與研究2組、3組比較,差異無統(tǒng)計學(xué)意義(P0.05);研究2組與研究3組相比較,單獨應(yīng)用自體羊膜或大黃、芒硝對降低瘢痕形成的差異不顯著,不具有統(tǒng)計學(xué)意義(P0.05); 2.研究1組隨訪中均為甲級愈合,其余三組組均存在數(shù)例乙級愈合,四組均無丙級愈合。研究1組與各組比較均有統(tǒng)計學(xué)意義(P0.05);研究2組、3組與對照組比較有差異(P0.05);但研究2組、3組間剖宮產(chǎn)皮膚切口愈合等級程度影響差異無統(tǒng)計學(xué)意義(P0.05)。 3.四組重度疼痛均為0例。研究1組與各組相比,明顯降低剖宮產(chǎn)皮膚切口疼痛程度。研究2組、3組與對照組比較有顯著差異(P0.05);單獨應(yīng)用羊膜組相比較于單獨應(yīng)用大黃、芒硝組剖宮產(chǎn)切口疼痛程度降低,差異具有統(tǒng)計學(xué)意義(P0.05)。 4.四組中均評分3分均為0例。研究1組與各組相比,明顯降低剖宮產(chǎn)皮膚切口腫脹程度。研究2組、3組與對照組比較有顯著差異(P0.05);單獨應(yīng)用大黃、芒硝組比單獨應(yīng)用羊膜組切口腫脹程度降低,差異具有統(tǒng)計學(xué)意義(P0.05)。 結(jié)論:羊膜聯(lián)合大黃、芒硝外敷切口顯著降低剖宮產(chǎn)皮膚切口疼痛、腫脹、瘢痕形成程度,有利于切口愈合。
[Abstract]:Background: in recent years, how to reduce pain and even without scar healing has been paid more and more attention by obstetricians and obstetricians. The Chinese medicine component Purple River car mainly comes from the fetal membrane in the placenta. It plays an important role in promoting the regeneration of epithelial stem cells and capillaries and reducing the important component of fibrotic factor in scar. The effect of the combination of amniotic membrane and rhubarb and Mirabilite in the healing of incisional incision is rarely reported at home and abroad. This study will discuss the important effect of amniotic membrane combined with rhubarb and mirabilite to promote the healing of incision of caesarean section.
Objective: To study the different treatment methods of caesarean section skin incision, use the postoperative incision pain, swelling degree, scar formation degree and incision healing grade to synthetically judge the healing of cesarean section, and discuss the effect of amniotic membrane combined with rhubarb and mirabilite to promote cesarean section healing.
Methods: a total of 400 healthy parturient women who were selected for cesarean section in the obstetrics department of Puyang oil field general hospital, January 2011, were randomly divided into 4 groups, 100 people in each group. The skin incision was only sutured and the skin was not sutured in all patients. The 1 groups were applied with autogenous amniotic membrane on the 1 groups, and 1 days after the operation, the incisions of mirabilite were applied straight to the incision. To the 5 day after the operation, the 2 groups were treated with autogenous amniotic membrane on the skin incision and conventional dressing after operation; the 3 groups were treated with routine dressing on the skin incision, 1 days after the operation with rhubarb and 5 days after the operation, and the 4 groups were treated with routine dressing after the skin incision and routine dressing change after operation.
Result錛,

本文編號:1875081

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