本文選題：細菌性陰道病 + 乳桿菌��； 參考：《現(xiàn)代生物醫(yī)學(xué)進展》2016年36期

【摘要】：目的:研究乳桿菌制劑在細菌性陰道病(bacterial vaginosis,BV)治療中的作用及其恢復(fù)陰道微生態(tài)平衡預(yù)防BV復(fù)發(fā)的價值,探討治療BV時應(yīng)用乳桿菌制劑的重要作用及恢復(fù)陰道微生態(tài)平衡的時間。方法:選取BV患者150例,隨機分為3組,A組單一給予抗生素治療;B組抗生素治療后補充乳桿菌制劑1療程;C組抗生素治療后補充乳桿菌制劑,每周評估陰道微生態(tài),直至重建陰道微生態(tài)平衡后停藥;三組停藥后均隨訪3個月。對比分析3種治療方案的臨床療效及復(fù)發(fā)情況。結(jié)果:3組治愈率均較高,為91.30%-95.73%,無統(tǒng)計學(xué)差異(P0.05);各隨訪階段累計復(fù)發(fā)率,B組和C組明顯低于A組,差異有統(tǒng)計學(xué)意義(P0.05);C組與B組相比,累計復(fù)發(fā)率更低;首發(fā)BV、有BV史BV、復(fù)發(fā)BV患者治療后重建陰道微生態(tài)平衡所需療程分別為3.53、5.18、7.43,有統(tǒng)計學(xué)差異(P0.01)。結(jié)論:單獨采用抗生素治療BV復(fù)發(fā)率高,聯(lián)合乳桿菌制劑治療后可以有效減低復(fù)發(fā)率,而適當(dāng)?shù)匮娱L乳桿菌治療時間徹底恢復(fù)陰道微生態(tài)平衡將顯著降低BV復(fù)發(fā)率;BV患者既往發(fā)生BV次數(shù)與重建陰道微生態(tài)平衡所需時間呈正相關(guān);因此,應(yīng)重視每一次BV治療。
[Abstract]:Objective: to study the role of lactobacillus preparation in the treatment of bacterial vaginosis (BV) and the value of restoring vaginal microecological balance to prevent the recurrence of BV, and to explore the important role of Lactobacillus preparation in the treatment of BV and the time to restore the vaginal microecological balance. Methods: one hundred and fifty patients with BV were randomly divided into three groups: group A was treated with antibiotics alone and group B was given lactobacillus after antibiotic treatment for one course of treatment and group C was supplemented with Lactobacillus after antibiotic treatment. The vaginal microecology was evaluated weekly. The three groups were followed up for 3 months. The clinical efficacy and recurrence of three treatment schemes were compared and analyzed. Results the cure rate of the three groups was higher (91.30-95.73C), there was no statistical difference (P0.05), the cumulative recurrence rate of group B and group C was significantly lower than that of group A (P 0.05), and the cumulative recurrence rate of group C was lower than that of group B (P 0.05), and that of group C (P 0.05) was lower than that of group B (P < 0.05), and the cumulative recurrence rate of group C was significantly lower than that of group B. The first course of treatment for patients with recurrent BV was 3.53 鹵5.187.43, and there was significant difference between the two groups (P < 0.01). The first BV had a history of BV, and the course of treatment for patients with recurrent BV was 3.53 鹵5.187.43, respectively. Conclusion: the recurrence rate of BV is high by using antibiotics alone, and the recurrence rate can be reduced effectively after treatment with lactobacillus preparation. However, prolonging the treatment time of Lactobacillus and restoring the vaginal microecological balance could significantly reduce the recurrence rate of BV and the time needed to reconstruct the vaginal microecological balance in BV patients. Therefore, we should pay attention to each BV treatment.
【作者單位】： 內(nèi)蒙古醫(yī)科大學(xué)附屬醫(yī)院婦產(chǎn)科;
【基金】：國家自然科學(xué)青年基金項目(81202730)
【分類號】：R711.31

【參考文獻】

相關(guān)期刊論文 前1條

1 李東燕;廖秦平;;細菌性陰道病發(fā)生的危險因素分析[J];中國微生態(tài)學(xué)雜志;2015年04期

【共引文獻】

相關(guān)期刊論文 前7條

1 朱sソ，

本文編號：1874152