本文選題：體外受精 + 拮抗劑方案��； 參考：《生殖醫(yī)學(xué)雜志》2013年10期

【摘要】：目的探討卵巢低反應(yīng)者行體外受精/卵胞漿內(nèi)單精子注射-胚胎移植(IVF/ICSI-ET)助孕治療時(shí),在拮抗劑方案中地屈孕酮預(yù)處理對(duì)卵泡均勻性的影響。方法分析促排卵前一月經(jīng)周期黃體中期行地屈孕酮預(yù)處理組(A組)73例和未行預(yù)處理對(duì)照組(B組)118例患者,對(duì)其月經(jīng)第2天(D2)卵泡刺激素(FSH)、黃體生成素(LH)、雌二醇(E_2),促性腺激素(Gn)天數(shù)、用量,拮抗劑天數(shù)、用量,注射人絨毛膜促性腺激素(HCG)日E_2、LH、孕激素(P)、子宮內(nèi)膜厚度、卵泡不同步率(將最大卵泡與次大卵泡平均直徑相差≥3 mm則視為不同步)、回收卵數(shù)、受精率、優(yōu)胚率、著床率、臨床妊娠率、繼續(xù)妊娠率等進(jìn)行對(duì)比觀察。結(jié)果與B組相比,A組D2 FSH下降[(7.75±4.03)vs.(9.28±4.08)IU/L,P=0.012];A組HCG日E_2增加L(4,593.39±2,334.35)vs.(3,784.94±2,065.36)pmol/L,P=0.013],回收卵數(shù)增加[(5.29±3.03)vs.(4.31±3.18)枚,P=0.036];A組Gn啟動(dòng)第7日卵泡不均勻率(16.44%vs.31.36%,P=0.022)及HCG日卵泡不均勻率(23.29%vs.37.29%,P=0.044)均下降。結(jié)論地屈孕酮預(yù)處理可促進(jìn)卵泡發(fā)育的均勻性。
[Abstract]:Objective to investigate the effect of diproprogesterone preconditioning on follicular homogeneity during IVF / ICSI-ETT in vitro fertilization / intracytoplasmic sperm injection (IVF / ICSI-ETT) in patients with low ovarian response. Methods 73 patients in group A and 118 patients in group B were treated with Diflexiprogesterone in the middle luteal phase of the first cycle before ovulation. On the 2nd day of menstruation, the days of follicle stimulating hormone (FSHN), luteinizing hormone (LHH), estradiol (E2N), gonadotropin (Gn), dosage, days of antagonist, dosage, E2LHH, progesterone, thickness of endometrium, and the day of injection of human chorionic gonadotropin (HCG) were studied. The average diameter difference between the largest follicle and the second big follicle was considered to be out of sync. The number of eggs recovered, fertilization rate, embryo rate, implantation rate, clinical pregnancy rate and continuous pregnancy rate were compared and observed. 緇撴灉涓嶣緇勭浉姣，

本文編號(hào)：1866238