本文選題：非肥胖型多囊卵巢綜合征 + 腎虛肝郁��； 參考：《中華中醫(yī)藥學(xué)刊》2015年02期

【摘要】：目的:觀察補腎調(diào)肝中藥復(fù)方對非肥胖型多囊卵巢綜合征(PCOS)患者性激素的影響。方法:采用前瞻性單盲隨機對照設(shè)計,選擇腎虛肝郁型非肥胖型PCOS(BMI25)患者60例,隨機分為治療組30例,采用毓麟珠和柴胡舒肝散治療3個月,每日1劑,早晚分服;對照組30例,選用二甲雙胍片(格華止):1000 mg,每日2次,早晚隨餐口服。對治療前后性激素水平、月經(jīng)周期,排卵率,妊娠率進行對比觀察。結(jié)果:1.治療3月后,兩組患者LH/FSH較前水平均有降低,以治療組降低明顯,P0.05;2.治療3月后,治療組LH較前有明顯降低,P0.05;對照組LH較前有降低,但無統(tǒng)計學(xué)差異;3.治療3月后,兩組月經(jīng)周期、排卵率及妊娠率均有改善,治療組療效優(yōu)于對照組,P0.05。結(jié)論:補腎調(diào)肝中藥復(fù)方以及二甲雙胍片均能改善非肥胖型多囊卵巢綜合征患者月經(jīng)周期,提高排卵率及妊娠率,可能是通過降低LH及LH/FSH起作用。
[Abstract]:Objective: to observe the effect of tonifying kidney and regulating liver compound on sex hormone in patients with non-obesity polycystic ovary syndrome (PCOS). Methods: a prospective, single blind randomized controlled design was used to select 60 patients with kidney deficiency and liver-depression type PCOSBMI25. They were randomly divided into treatment group (n = 30) and control group (n = 30) treated with Yulin Zhu and Chaihu Shugan Powder for 3 months, 1 dose per day, in the morning and evening, and 30 patients in the control group. Take metformin tablet twice a day, morning and evening with meal. Sex hormone level, menstrual cycle, ovulation rate and pregnancy rate before and after treatment were observed. The result is 1: 1. After 3 months of treatment, the LH/FSH level in both groups was lower than that in the former group, especially in the treatment group. After 3 months of treatment, LH in the treatment group was significantly lower than that in the former group (P 0.05), while in the control group it was lower than that in the former group, but there was no statistical difference between the two groups. After 3 months of treatment, the menstrual cycle, ovulation rate and pregnancy rate of the two groups were improved, and the curative effect of the treatment group was better than that of the control group (P 0.05). Conclusion: both prescription of tonifying kidney and regulating liver and metformin tablets can improve menstrual cycle, increase ovulation rate and pregnancy rate in patients with non-obese polycystic ovary syndrome, which may be due to the decrease of LH and LH/FSH.
【作者單位】： 浙江省中西醫(yī)結(jié)合醫(yī)院;杭州師范大學(xué);黑龍江中醫(yī)藥大學(xué)附屬第一醫(yī)院;
【基金】：浙江省中醫(yī)藥管理局青年基金項目(ZQ2010012)
【分類號】：R711.75

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