六氟化硫微泡在HIFU治療T2WI高信號(hào)子宮肌瘤中的臨床應(yīng)用
發(fā)布時(shí)間:2018-05-02 22:13
本文選題:子宮肌瘤 + 超聲消融; 參考:《昆明醫(yī)科大學(xué)學(xué)報(bào)》2016年11期
【摘要】:目的探討六氟化硫微泡在高強(qiáng)度聚焦超聲治療T2高信號(hào)子宮肌瘤中的應(yīng)用價(jià)值.方法選取昆明醫(yī)科大學(xué)第一附屬醫(yī)院36例單發(fā)T2高信號(hào)子宮肌瘤患者隨機(jī)分成研究組和對(duì)照組,對(duì)照組18例患者術(shù)中不用六氟化硫微泡,研究組18例患者術(shù)中使用六氟化硫微泡.分別記錄2組的手術(shù)時(shí)間(min)、出現(xiàn)塊狀灰度變化時(shí)間(s)、輻照時(shí)間(s)、治療劑量(J),并發(fā)癥發(fā)生的情況及消融率(%).結(jié)果研究組手術(shù)時(shí)間、出現(xiàn)塊狀灰度變化時(shí)間(s)、輻照時(shí)間(s)、治療劑量分別為(101.51±43.02)min,(856.42±451.14)s,(1077.37±546.23)s,(496 581.81±267 192.31)J,對(duì)照組分別為(261.34±85.53)min,(1 833.32±642.67)s,(1 890.21±1 268.43)s,(784 608.31±357 621.45)J,2組各參數(shù)相比差異有統(tǒng)計(jì)學(xué)意義(P0.05).研究組消融率為83.3%,對(duì)照組消融率為55.5%,2組參數(shù)相比差異有統(tǒng)計(jì)學(xué)意義(P0.05).研究組患者出現(xiàn)全身麻木1例,沒(méi)有發(fā)生治療區(qū)皮膚燒傷.對(duì)照組治療區(qū)皮膚Ⅱ°燒傷1例,全身麻木2例,并發(fā)癥的發(fā)生率為1/18(5.5%),2組均未出現(xiàn)腸穿孔、膀胱穿孔等嚴(yán)重并發(fā)癥.結(jié)論六氟化硫微泡在高強(qiáng)度聚焦超聲熱消融T2高信號(hào)子宮肌瘤中可縮短手術(shù)時(shí)間,減少并發(fā)癥,提高消融率,在臨床中發(fā)揮著重要的應(yīng)用價(jià)值.
[Abstract]:Objective to evaluate the value of sulfur hexafluoride microbubbles in the treatment of T 2 hysteromyoma with high intensity focused ultrasound (HIFU). Methods Thirty-six patients with single T2 hyperintense hysteromyoma were randomly divided into two groups: the control group (n = 18) and the control group (n = 18). In the study group, 18 patients were treated with sulfur hexafluoride microbubbles during operation. The operation time, time of massive gray scale change, irradiation time, therapeutic dose, complications and ablation rate were recorded in the two groups. Results in the study group, the operation time, the time of massive gray scale change and the irradiation time were 101.51 鹵43.02min, 856.42 鹵451.14min, 1077.37 鹵546.23, 496 鹵581.81 鹵262.31 and 261.34 鹵85.53min respectively. There were significant differences between the two groups (P 0.05). The ablation rate was 83.3 in the study group and 55.5 in the control group. One case of systemic numbness occurred in the study group, and no skin burn occurred in the treatment area. In the control group, there were 1 case of skin 鈪,
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