成都地區(qū)58650例女性宮頸人乳頭瘤病毒感染狀況調查
發(fā)布時間:2018-05-02 09:17
本文選題:人乳頭狀瘤病毒 + 基因分布; 參考:《山東醫(yī)藥》2017年26期
【摘要】:目的了解成都地區(qū)女性宮頸脫落細胞人乳頭瘤病毒(HPV)感染狀況和基因分布特征,為本地區(qū)女性HPV感染提供流行病學依據(jù)。方法采集成都地區(qū)58 650例女性宮頸脫落細胞,采用HPV基因分型方法檢測23種HPV基因型的分布、年齡特征、感染模式。結果 58 650例女性中,感染HPV 12 399例,HPV陽性率為21.14%。其中高危型、低危型、高危和低;旌细腥拘突颊叻謩e占71.81%、12.16%、16.03%。18種高危型HPV的感染率由高到低依次為52、16、58、53、51、68、56、18、59、33、66、39、31、35、45、83、73、82,5種低危型HPV的感染率由高到低依次為81、43、42、6、11。總感染率、高危型感染率、高低混合型感染率、多重感染率的感染高峰年齡段均為20歲和≥60歲,30~50歲年齡段感染率最低;低危型感染率和一重感染率的高峰年齡段均為≤20歲。HPV感染模式中單一感染占72.30%,多重感染占27.70%(以二重感染為主)。20歲和≥60歲年齡段患者以多重感染為主。結論成都地區(qū)女性HPV基因分型感染率隨年齡呈U形分布;應加強對20歲和≥60歲女性HPV感染的監(jiān)測。
[Abstract]:Objective to investigate the status and gene distribution of human papillomavirus (HPV) infection in female cervical exfoliated cells in Chengdu, and to provide epidemiological basis for female HPV infection in Chengdu. Methods 58 650 female cervical exfoliated cells were collected from Chengdu area. The distribution, age characteristics and infection pattern of 23 HPV genotypes were detected by HPV genotyping. Results among 58,650 women, the positive rate of HPV infection was 21.14% in 12 399 cases. Among them, high risk type, low risk type, high risk type and low risk mixed infection type accounted for 71.81% and 12.16%, 12.16% and 16.03.18 kinds of high risk type HPV infection rate was 52O1655C53O516165C5O6639331A35555555555555555A455A455A73N73N82P from high to low in turn from high to low, the infection rate of HPV from high to low was 81ng / 4226611a (P < 0.05). The infection rate of high risk type, high risk type and low risk type of HPV was 71.81%, 12.16%, 12.16%, 12.16% and 12.16%, respectively. The total infection rate, high risk type infection rate, high and low mixed infection rate, the peak infection age of multiple infection rate were 20 years old and 鈮,
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