發(fā)布時(shí)間：2018-04-26 19:39

  本文選題：液基薄層細(xì)胞學(xué) + 陰道鏡活檢HPV檢測(cè)��； 參考：《中國繼續(xù)醫(yī)學(xué)教育》2016年33期

【摘要】：目的探討TCT檢查、HPV檢測(cè)、陰道鏡宮頸活檢、LEEP術(shù)在子宮頸上皮內(nèi)瘤病變中臨床意義。方法 2011年9月~2015年1月在連云港市第一人民醫(yī)院就診的患者共2 146例,術(shù)前常規(guī)行TCT檢查,338例患者在陰道鏡下宮頸活檢之后,提示宮頸上皮內(nèi)高度病變,行環(huán)形電切術(shù)治療,標(biāo)本行病理學(xué)檢查。結(jié)果 (1)2 146例患者TCT檢查,308例異常占14.35%;其中97例ASCUS占31.49%;153例LSIL占49.68%;49例HSIL占15.91%;9例SCC占2.92%。(2)TCT與LEEP術(shù)后病理比較,TCT陽性報(bào)告者中CIN及宮頸癌檢出率為83.12%。LSIL診斷符合率62.75%,HSIL診斷符合率85.71%,LSIL與HSIL診斷符合率的差異有統(tǒng)計(jì)學(xué)意義(χ2=5.82,P0.05)。(3)HPV檢測(cè)及聯(lián)合TCT檢測(cè)結(jié)果:CIN檢出率93.53%,其中CINⅡ~Ⅲ檢出率為50.86%。(4)338例LEEP術(shù)后病理與陰道鏡活檢病理診斷符合率為66.56%。結(jié)論 TCT是宮頸疾病篩查的主要方法,HPV陽性篩查率與病理級(jí)別呈正相關(guān),TCT與HPV聯(lián)合檢測(cè)能提高宮頸病變檢出率,對(duì)宮頸癌早期發(fā)現(xiàn)有指導(dǎo)意義;宮頸活檢不易檢查出子宮頸深部組織及頸管內(nèi)病變,LEEP術(shù)既能有效診斷子宮頸病變,同時(shí)有治療作用。
[Abstract]:Objective to investigate the clinical significance of TCT in cervical intraepithelial neoplasia. Methods from September 2011 to January 2015, a total of 2 146 patients were admitted to Lianyungang first people's Hospital. Preoperative TCT examination was performed in 338 patients with cervical biopsy under colposcopy. The specimens were examined by pathology. Results among the 2 146 patients with TCT, 308 cases were abnormal in TCT examination and 97 cases with ASCUS accounted for 31.49 cases. 153 cases with LSIL and 49 cases with HSIL accounted for 15.91%. The positive rate of CIN and cervical cancer was 62.75 HSIL diagnostic coincidence rate between 2.92%.(2)TCT and LEEP. The diagnostic coincidence rate between LSIL and HSIL was statistically significant (蠂 ~ (2) ~ (5.82) (蠂 ~ (2 +) 5.82) and combined TCT examination. The detection rate of CIN 鈪，

本文編號(hào)：1807425