本文選題：妊娠晚期　切入點：B族溶血性鏈球菌　出處：《中華醫(yī)院感染學雜志》2017年19期

【摘要】：目的探究妊娠晚期孕婦B族溶血性鏈球菌感染對孕產(chǎn)婦凝血功能及母嬰結(jié)局的影響。方法選擇2014年12月-2015年10月在醫(yī)院產(chǎn)檢的孕婦320例,均經(jīng)B超檢查進行確認、核對,依據(jù)孕婦是否存在B族溶血性鏈球菌感染將其劃分為B族溶血性鏈球菌感染陽性組29例,陰性組58例(依據(jù)其就診時ID號碼,從291例B族溶血性鏈球菌陰性的產(chǎn)婦中隨機選擇58例),觀察凝血功能及母嬰結(jié)局。結(jié)果 320例孕婦中檢測出B族溶血性鏈球菌感染陽性患者29例,陽性率為9.06%;陽性組除血漿凝血酶時間(TT)外,血漿凝血酶原時間(PT)(9.67±1.13)s、國際標準化比率(INR)(0.95±0.07)及活化部分凝血活酶時間(APTT)(25.69±3.65)s與陰性組比較均明顯縮短,而纖維蛋白原(Fbg)(3.89±1.68)g/L與陰性組比較明顯增高(P0.05);29例感染陽性孕婦中2例發(fā)生胎膜早破,發(fā)生率6.90%,58例陰性孕婦中3例發(fā)生胎膜早破,發(fā)生率5.17%,兩組無統(tǒng)計學差異;陽性組孕婦剖宮產(chǎn)率和胎兒窘迫發(fā)生率、新生兒窒息發(fā)生率和病理學黃疸發(fā)生率,明顯高于陰性組(P0.05)。結(jié)論密切觀察B族溶血性鏈球菌感染孕婦的凝血功能情況,可在一定程度上預防彌散性血管內(nèi)凝血(DIC)出血性疾病,同時對妊娠晚期孕婦給予適量抗菌藥物,對于降低妊娠孕婦和新生兒相關(guān)并發(fā)癥,保證孕婦和新生兒的生命安全具有重要意義。
[Abstract]:Objective to investigate the effect of group B hemolytic streptococcus infection on coagulation function and maternal and infant outcome of pregnant women in the third trimester of pregnancy.Methods 320 pregnant women born in hospital from December 2014 to October 2015 were selected and confirmed by B-ultrasound. According to whether the pregnant women had Group B hemolytic streptococcus infection, they were divided into 29 cases of Group B hemolytic Streptococcus infection positive group.58 cases of negative group (according to their ID number) were randomly selected from 291 cases of group B hemolytic streptococcus negative puerpera to observe the coagulation function and the outcome of mother and child.Results 29 cases of Group B hemolytic streptococcus infection were detected in 320 pregnant women, the positive rate was 9.06.The positive group except plasma thrombin time (TTT),The incidence of premature rupture of membranes in 3 out of 58 negative pregnant women was 5.170.There was no statistical difference between the two groups, and the rate of cesarean section, fetal distress, neonatal asphyxia and pathological jaundice in the positive group was significantly higher than that in the negative group (P 0.05).Conclusion to observe the coagulation function of pregnant women with B group hemolytic streptococcus infection can prevent the disseminated intravascular coagulation (DICD) hemorrhagic disease to some extent, and at the same time, give appropriate amount of antibiotics to the pregnant women in the third trimester of pregnancy.It is of great significance to reduce the complications of pregnant women and newborns and to ensure the safety of pregnant women and newborns.
【作者單位】： 儋州市人口和計劃生育服務中心;儋州市婦幼保健院婦產(chǎn)科;
【分類號】：R714.251

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