本文選題：宮頸上皮內(nèi)瘤變　切入點(diǎn)：宮頸錐切術(shù)　出處：《中國(guó)婦幼健康研究》2014年02期

【摘要】：目的探討宮頸上皮內(nèi)瘤變患者行宮頸錐形切除術(shù)對(duì)妊娠結(jié)局、分娩結(jié)局的影響。方法計(jì)算機(jī)檢索Cochrane Library、PubMed、SCI及萬(wàn)方、CNKI、CBM等數(shù)據(jù)庫(kù)并輔以手工檢索相關(guān)期刊,檢索時(shí)間至2013年3月。由兩名研究者獨(dú)立篩選文獻(xiàn)、提取資料及方法學(xué)質(zhì)量評(píng)價(jià),用RevMan 5.1.7軟件進(jìn)行Meta分析。結(jié)果共納入病例-對(duì)照試驗(yàn)11篇,包括721例病例組與5565對(duì)照組。Meta分析結(jié)果顯示:與未行宮頸錐切的正常人群相比,宮頸錐切手術(shù)對(duì)治療年輕有生育要求的宮頸上皮內(nèi)瘤變分娩時(shí)宮頸裂傷的發(fā)生率無(wú)統(tǒng)計(jì)學(xué)意義(OR=2.15,95%CI:0.51~9.09,P=0.30),妊娠率無(wú)統(tǒng)計(jì)學(xué)意義(OR=1.02,95%CI:0.59~1.76,P=0.94),分娩方式(剖宮產(chǎn)或陰道分娩)上無(wú)統(tǒng)計(jì)學(xué)意義(OR=1.04,95%CI:0.86~1.27,P=0.06),流產(chǎn)的發(fā)生率無(wú)統(tǒng)計(jì)學(xué)意義(OR=1.34,95%CI:0.81~2.23,P=0.26)。但在早產(chǎn)率(OR=2.16,95%CI:1.56~2.99,P0.00001)、胎膜早破的發(fā)生率(OR=2.82,95%CI:1.70~4.67,P0.00001)、新生兒低體重兒的發(fā)生率(OR=2.62,95%CI:1.62~4.24,P0.00001)等方面有統(tǒng)計(jì)學(xué)意義。結(jié)論與未行宮頸錐切的正常人群相比,宮頸錐切手術(shù)對(duì)術(shù)后妊娠率、分娩方式、宮頸裂傷以及流產(chǎn)率無(wú)影響,但會(huì)增加術(shù)后早產(chǎn)、胎膜早破及低出生體重兒的發(fā)生率。
[Abstract]:Objective to investigate the effect of cervical conical resection on pregnancy outcome and delivery outcome in patients with cervical intraepithelial neoplasia.Methods the databases such as Cochrane Library PubMedi sci and CNKI CBM were searched by computer and the related journals were retrieved manually until March 2013.Two researchers independently sifted literature, extracted data and evaluated the quality of methodology. Meta analysis was carried out with RevMan 5.1.7 software.Results A total of 11 case-control trials were included, including 721 cases and 5565 controls. Meta-analysis showed that: compared with the normal population without cervical conization,瀹閿ュ垏鎵嬫湳瀵規(guī)不鐤楀勾杞繪湁鐢熻偛瑕佹眰鐨勫棰堜笂鐨唴鐦ゅ彉鍒嗗ī鏃跺棰堣浼ょ殑鍙戠敓鐜囨棤緇熻瀛︽剰涔，

本文編號(hào)：1710126