本文選題：宮頸鱗狀上皮內(nèi)瘤變　切入點(diǎn)：宮頸錐切術(shù)　出處：《中華腫瘤防治雜志》2017年01期

【摘要】：目的宮頸癌篩查的普及極大地提高了宮頸癌前病變的檢出率,而病理診斷對(duì)宮頸癌前病變的診療至關(guān)重要,癌前病變的精確病理分級(jí)對(duì)于宮頸癌前病變治療效果的評(píng)價(jià)和治療方法的選擇具有重要意義。本研究旨在探討宮頸鱗狀上皮內(nèi)瘤變(cervical intraepithelial neoplasia,CIN)Ⅱ和Ⅲ級(jí)病變采用環(huán)形電切除術(shù)(loop electrosurgical excision procedure,LEEP)和宮頸冷刀錐切術(shù)(cold knife conization,CKC)前后,病理分級(jí)變化及其對(duì)CIN的診斷治療作用。方法選擇2015-01-01-2015-12-31在靖江市中醫(yī)院就診的經(jīng)陰道鏡多點(diǎn)活檢病理確診的CINⅡ和CINⅢ患者149例,隨機(jī)數(shù)字表法分為L(zhǎng)EEP組75例和CKC組74例,觀察手術(shù)前后病理檢查的符合度和病理降級(jí)、升級(jí)率。結(jié)果陰道鏡多點(diǎn)活檢與LEEP術(shù)后CIN病理符合率為56.00%(42/75),LEEP術(shù)后病理降級(jí)率為21.33%(16/75),病理升級(jí)率為22.67%(17/75)。陰道多點(diǎn)活檢與CKC后CIN病理符合率為66.22%(49/74),病理升級(jí)率為12.16%(9/74),病理降級(jí)率為21.62%(16/74)。宮頸冷刀錐切術(shù)和LEEP術(shù)后病理與術(shù)前病理符合率、病理升級(jí)率、病理降級(jí)率比較差異均無(wú)統(tǒng)計(jì)學(xué)意義,P0.05;復(fù)發(fā)率差異無(wú)統(tǒng)計(jì)學(xué)意義,P0.05。結(jié)論 CINⅡ和CINⅢ級(jí)病變LEEP術(shù)和CKC術(shù)后病理結(jié)果無(wú)差異,具有相同的治愈率。建議根據(jù)臨床及患者意愿選擇治療方法。
[Abstract]:Objective the prevalence of cervical cancer screening has greatly increased the detection rate of cervical precancerous lesions, and pathological diagnosis is very important to the diagnosis and treatment of cervical precancerous lesions. The accurate pathological grading of precancerous lesions is of great significance for the evaluation of the therapeutic effect and the choice of treatment methods for cervical precancerous lesions. This study was designed to investigate the use of ring ring in cervical squamous intraepithelial neoplasia (Cervical intraepithelial neoplasia cin) 鈪，

本文編號(hào)：1674101