HCG日孕酮水平與體外受精-胚胎移植治療結(jié)局的關(guān)系探討
發(fā)布時(shí)間:2018-03-27 05:14
本文選題:HCG日 切入點(diǎn):孕酮濃度 出處:《暨南大學(xué)學(xué)報(bào)(自然科學(xué)與醫(yī)學(xué)版)》2017年02期
【摘要】:目的:探討在體外受精-胚胎移植(IVF-ET)控制性促排卵(COH)過(guò)程中,人絨毛膜促性腺激素(HCG)日孕酮(P)濃度與IVF-ET治療結(jié)局的關(guān)系.方法:分析350個(gè)IVF-ET取卵周期,均采用黃體中期垂體降調(diào)節(jié)方案,按HCG日血清孕酮濃度分為3組,分別為A組67例(1.0≤P2.0 nmol/L)、B組133例(2.0≤P3.0 nmol/L)、C組150例(3.0≤P4.77 nmol/L).比較3組患者的基本臨床資料、卵子及胚胎資料、周期取消及妊娠結(jié)局情況.結(jié)果:HCG日血清孕酮濃度在3.0~4.77 nmol/L組時(shí),獲卵數(shù)、MII卵數(shù)及受精數(shù)均高于其他組;同時(shí)種植率及妊娠率亦最高.結(jié)論:HCG日血清孕酮濃度水平在3.0~4.77 nmol/L之間能獲得更成熟的卵子,同時(shí)不增加因多卵泡發(fā)育引起卵巢過(guò)度刺激綜合征(OHSS)導(dǎo)致的周期取消率.
[Abstract]:Objective: to investigate the relationship between the concentration of human chorionic gonadotropin (HCG) day progesterone and the outcome of IVF-ET during IVF-ET-controlled ovulation induction during in vitro fertilization and embryo transfer. All patients were divided into three groups according to the serum progesterone concentration of HCG day, which were divided into three groups: group A, 67 cases (group A, n = 67) with 1.0 鈮,
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