本文選題：盆腔炎　切入點(diǎn)：支原體感染　出處：《中華中醫(yī)藥學(xué)刊》2017年08期

【摘要】：目的:探討多西環(huán)素聯(lián)合盆腔炎2號(hào)方治療支原體感染盆腔炎療效及安全性分析。方法:選擇2015年1月—2016年6月期間于醫(yī)院就診收治的支原體感染盆腔炎患者80例為研究對(duì)象,根據(jù)隨機(jī)數(shù)字表法將兩組患者均分為觀察組與對(duì)照組各40例,其中對(duì)照組患者單獨(dú)給予多西環(huán)素治療,觀察組患者在對(duì)照組的基礎(chǔ)上聯(lián)合應(yīng)用盆腔炎2號(hào)方治療,常規(guī)治療后比較兩組患者的臨床治療效果、治療期間的不良反應(yīng)情況以及患者子宮血流動(dòng)力學(xué)指標(biāo)指標(biāo)之間的差異情況。結(jié)果:兩組患者治療后,其中觀察組患者的臨床治愈患者例數(shù)27例、治愈率67.5%,明顯的高于對(duì)照組患者的19例、47.5%,兩組比較差異有統(tǒng)計(jì)學(xué)意義(P0.05),可以比較;觀察組患者的臨床治療無(wú)效例數(shù)1例、無(wú)效率2.5%,明顯的低于對(duì)照組患者的6例、15.0%,兩組比較差異有統(tǒng)計(jì)學(xué)意義(P0.05),可以比較;觀察組患者治療期間頭暈頭痛患者2例、惡心嘔吐2例、腹瀉0例、肝功能異常1例,明顯的低于對(duì)照組患者的頭暈頭痛患者5例、惡心嘔吐4例、腹瀉5例、肝功能異常3例,兩組比較差異有統(tǒng)計(jì)學(xué)意義(P0.05),可以比較;觀察組患者的阻力指數(shù)(RI)0.86±0.03、搏動(dòng)指數(shù)(PI)2.49±0.09以及平均血流速度(Vmin)0.60±0.03,明顯的高于對(duì)照組患者的阻力指數(shù)(RI)0.80±0.02、搏動(dòng)指數(shù)(PI)2.20±0.06以及平均血流速度(Vmin)0.41±0.02,兩組比較差異有統(tǒng)計(jì)學(xué)意義(P0.05),可以比較。結(jié)論:多西環(huán)素聯(lián)合盆腔炎2號(hào)方在支原體感染盆腔炎的臨床治療過(guò)程中,具有較好的臨床治療效果以及安全性,治療期間的藥物不良反應(yīng)情況發(fā)生率低,可以有效地改善患者的血流動(dòng)力學(xué)指標(biāo),在臨床上具有極高應(yīng)用價(jià)值,值得進(jìn)一步推廣使用。
[Abstract]:Objective: to investigate the efficacy and safety of doxycycline combined with pelvic inflammatory prescription No. 2 in the treatment of mycoplasma infection with pelvic inflammatory disease. Methods: 80 patients with mycoplasma infection were selected from January 2015 to June 2016. According to the method of random number table, the two groups were divided into observation group (n = 40) and control group (n = 40). The patients in the control group were treated with doxycycline alone, and the patients in the observation group were treated with pelvic inflammatory prescription No. 2 on the basis of the control group. After routine treatment, the clinical efficacy, adverse reactions during treatment and the difference of uterine hemodynamic indexes were compared between the two groups. There were 27 cases of clinical cure in the observation group, and the cure rate was 67.5%, which was significantly higher than that in the control group (19 cases, 47.5%). The difference between the two groups was statistically significant (P 0.05). The effective rate was 2.5, which was significantly lower than that in the control group (6 cases, 15.0%), and the difference between the two groups was statistically significant (P 0.05), and there were 2 cases of dizziness and headache, 2 cases of nausea and vomiting, 0 cases of diarrhea and 1 case of abnormal liver function in the observation group. There were 5 cases of dizziness and headache, 4 cases of nausea and vomiting, 5 cases of diarrhea and 3 cases of abnormal liver function. The difference between the two groups was statistically significant (P 0.05). The resistance index (RI), pulsatile index (Pi) and mean blood flow velocity (Vmin) of the patients in the observation group were 0.86 鹵0.03, 2.49 鹵0.09 and 0.60 鹵0.03, respectively, which were significantly higher than those in the control group (0.80 鹵0.02), PII (2.20 鹵0.06) and Vmin (0.41 鹵0.02). The difference between the two groups was statistically significant. Conclusion: doxycycline combined with pelvic inflammatory recipe No. 2 in the clinical treatment of mycoplasma infection of pelvic inflammatory disease, It has good clinical effect and safety, low incidence of adverse drug reactions during the treatment, can effectively improve the hemodynamic index of patients, has a very high clinical application value, worthy of further promotion and use.
【作者單位】： 海南醫(yī)學(xué)院第二附屬醫(yī)院婦產(chǎn)科;
【基金】：海南省衛(wèi)計(jì)委項(xiàng)目(1421320.31A2004)
【分類號(hào)】：R711.33

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