本文選題：妊娠期糖尿病　切入點(diǎn)：催產(chǎn)素　出處：《重慶醫(yī)學(xué)》2015年07期 　論文類型：期刊論文

【摘要】：目的探討靜脈滴注催產(chǎn)素對(duì)妊娠期糖尿病(GDM)產(chǎn)婦引產(chǎn)過程中滴速的調(diào)控方法以及GDM對(duì)催產(chǎn)素敏感性的影響。方法選擇靜脈滴注催產(chǎn)素引產(chǎn)的GDM初產(chǎn)婦196例為GDM組,同期經(jīng)催產(chǎn)素引產(chǎn)的非GDM初產(chǎn)婦371例為對(duì)照組。各組根據(jù)不同的輸注濃度(5、10mU/mL)及滴速調(diào)節(jié)方式(等差/等比)分別分為A1、A2、B1、B2組。對(duì)比分析各組引產(chǎn)開始至最佳有效宮縮時(shí)間、催產(chǎn)素用量、引產(chǎn)成功率、新生兒窒息率以及不良反應(yīng)發(fā)生率。結(jié)果 GDM組至最佳宮縮時(shí)間A1組最長(zhǎng),B2組最短,A2組顯著長(zhǎng)于B2組(P0.05);與對(duì)照組比較,濃度及滴速相同情況下GDM組至最佳宮縮時(shí)間均分別顯著長(zhǎng)于對(duì)照組(P0.05),催產(chǎn)素用量顯著高于對(duì)照組(P0.05)。結(jié)論 GDM會(huì)降低產(chǎn)婦對(duì)催產(chǎn)素引產(chǎn)的敏感性,催產(chǎn)素以10mU/mL、8滴/min起、等比遞增調(diào)控是安全有效的調(diào)控模式。
[Abstract]:Objective to investigate the effect of intravenous oxytocin on the rate of induced labor in pregnant women with diabetes mellitus (GDM) and the effect of GDM on the sensitivity of oxytocin. Methods 196 cases of GDM primipara who were induced by oxytocin were selected as GDM group. At the same time, 371 cases of non-#en0# primipara induced by oxytocin were divided into two groups according to different infusion concentration (510mU / mL) and droplet velocity regulation (equal difference / equal ratio). The time from induction of labor to optimal effective uterine contraction in each group was compared and analyzed. Results the dosage of oxytocin, the success rate of induced labor, the rate of asphyxia neonatorum and the incidence of adverse reactions were significantly longer in group A _ 2 than in group A _ 2 and group A _ 2 from group A _ 1 to group A _ 2.Compared with the control group, there was no significant difference between group A _ 2 and group B _ 2. Under the same concentration and droplet rate, the optimal uterine contraction time of GDM group was significantly longer than that of control group (P 0.05), and the dosage of oxytocin was significantly higher than that of control group (P 0.05). Conclusion GDM can decrease the sensitivity of parturient to oxytocin induction. Increasing equal ratio regulation is a safe and effective regulation mode.
【作者單位】： 海南醫(yī)學(xué)院附屬醫(yī)院產(chǎn)科;
【分類號(hào)】：R714.256

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