妊娠合并二尖瓣狹窄孕婦54例的臨床分析
發(fā)布時(shí)間:2018-03-06 16:51
本文選題:二尖瓣狹窄 切入點(diǎn):心血管 出處:《中國(guó)婦產(chǎn)科臨床雜志》2017年01期 論文類(lèi)型:期刊論文
【摘要】:目的 探討妊娠合并二尖瓣狹窄的孕婦在妊娠期的臨床處理方法和母兒安全性。方法 回顧性分析2008年1月至2016年2月首都醫(yī)科大學(xué)附屬北京安貞醫(yī)院54例妊娠合并二尖瓣狹窄的孕婦的臨床資料,包括孕周、二尖瓣狹窄程度、孕期的管理和治療及母兒結(jié)局。結(jié)果 (1)臨床特點(diǎn):54例患者中輕度狹窄9例,中度狹窄10例,重度狹窄35例,年齡25~34歲,發(fā)病孕周12~38周,臨床表現(xiàn):二尖瓣面容,勞力性呼吸困難,聽(tīng)診舒張期隆隆樣雜音,二尖瓣型P波;心臟并發(fā)癥:肺動(dòng)脈高壓、心律失常、肺水腫、心內(nèi)膜炎、心力衰竭、死亡等;(2)重度狹窄與輕、中度狹窄在孕婦心臟并發(fā)癥和胎兒/新生兒并發(fā)癥的差異有統(tǒng)計(jì)學(xué)意義(P0.05);(3)二尖瓣狹窄的孕婦中輕度和中度狹窄,通過(guò)藥物治療,重度二尖瓣狹窄需經(jīng)皮介入性球囊擴(kuò)張術(shù)和心臟外科手術(shù)治療。結(jié)論 妊娠合并二尖瓣狹窄,特別是重度二尖瓣狹窄,應(yīng)孕前咨詢,及時(shí)干預(yù),可改善母兒預(yù)后。
[Abstract]:Objective to investigate the clinical management and maternal and fetal safety of pregnant women with mitral stenosis during pregnancy. Methods 54 cases of pregnancy in Beijing Anzhen Hospital affiliated to Capital Medical University from January 2008 to February 2016 were retrospectively analyzed. Clinical data of pregnant women with mitral stenosis, Results 1) Clinical features: 9 cases of mild stenosis, 10 cases of moderate stenosis, 35 cases of severe stenosis, age 250-34 years, onset of gestational age 1238 weeks, clinical features of 9 cases of mild stenosis, 10 cases of moderate stenosis, 35 cases of severe stenosis, and the management and treatment of mitral valve stenosis during pregnancy and pregnancy. Clinical manifestations: mitral valve appearance, exertional dyspnea, auscultation diastolic rumbling murmur, mitral valve P wave, cardiac complications: pulmonary hypertension, arrhythmia, pulmonary edema, endocarditis, heart failure, There was significant difference between severe stenosis and mild and moderate stenosis in pregnant women and fetal / neonatal complications. There was a significant difference between severe stenosis and mild or moderate stenosis in pregnant women with mitral stenosis, and the difference was statistically significant in pregnant women with fetal / neonatal complications (P < 0.05). The patients with mitral stenosis had mild and moderate stenosis and were treated with drugs. Conclusion pregnancy complicated with mitral stenosis, especially severe mitral stenosis, should be treated with pre-pregnancy consultation and timely intervention, which can improve the prognosis of mother and infant.
【作者單位】: 首都醫(yī)科大學(xué)附屬北京安貞醫(yī)院婦產(chǎn)科;首都醫(yī)科大學(xué)附屬北京安貞醫(yī)院心臟科;
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