本文選題：外陰營(yíng)養(yǎng)不良　切入點(diǎn)：流行病學(xué)　出處：《四川大學(xué)學(xué)報(bào)(醫(yī)學(xué)版)》2017年05期 　論文類型：期刊論文

【摘要】：目的了解四川地區(qū)外陰營(yíng)養(yǎng)不良的基本流行病學(xué)數(shù)據(jù),同時(shí)比較其兩種亞型(單純性苔蘚型和硬化性苔蘚型)電生理治療的可行性及效果。方法對(duì)2010~2015年在四川大學(xué)華西第二醫(yī)院門(mén)診診斷為外陰營(yíng)養(yǎng)不良的患者進(jìn)行橫斷面調(diào)查;同時(shí)采用前瞻性隊(duì)列研究的方法,納入2015年1~12月在本院經(jīng)病理活檢證實(shí)為外陰營(yíng)養(yǎng)不良的患者26例(單純性苔蘚型18例和硬化性苔蘚型8例),采集臨床數(shù)據(jù),包括瘙癢量表評(píng)分和皮膚狀態(tài)評(píng)估,由專人采用統(tǒng)一方法進(jìn)行電生理治療,記錄治療前后疾病狀態(tài)的變化。結(jié)果 (1)2010~2015年我院婦科門(mén)診診斷為外陰營(yíng)養(yǎng)不良的患者為33 859例,患病率為1.38%;(2)成都地區(qū)(13 870例,40.96%)及川南地區(qū)(6 333例,18.70%)患病人群明顯多于其它地區(qū);城鎮(zhèn)患者(22 998例,67.92%)明顯多于農(nóng)村患者(10 861例,32.08%);(3)除了40~50歲年齡段,單純性苔蘚及硬化性苔癬患病率在其它不同年齡段間的差異均有統(tǒng)計(jì)學(xué)意義(P0.05)。兩組患者經(jīng)電生理治療后隨訪6~12個(gè)月,外陰皮膚顏色改善18例(69.23%),瘙癢評(píng)分改善22例(84.62%);其中單純性苔蘚組治療有效率為88.89%(16例),硬化性苔蘚組治療有效率為50.00%(4例),兩組間有效率的差異有統(tǒng)計(jì)學(xué)意義(P0.01)。結(jié)論外陰營(yíng)養(yǎng)不良在四川地區(qū)相對(duì)常見(jiàn),且發(fā)病具有一定的區(qū)域差異;單純性苔蘚型患者更為年輕,且電生理治療效果更好。
[Abstract]:Objective to understand the basic epidemiological data of vulvar malnutrition in Sichuan Province. At the same time, the feasibility and effect of electrophysiological therapy of two subtypes (simple mossy and sclerosing lichen) were compared. Methods A cross-sectional survey was carried out on the patients diagnosed as vulvar dystrophy in the outpatient clinic of West China Hospital of Sichuan University from 2010 to 2015. At the same time, a prospective cohort study was used to collect clinical data from 26 patients with vulvar dystrophy (18 cases of simple lichen type and 8 cases of sclerosing lichen type) confirmed by pathological biopsy in our hospital from 2015 to December. Including the scale of pruritus and the evaluation of skin condition, the patients were treated by electrophysiologic therapy with unified method. Results from 2010 to 2015, 33,859 patients with vulvar dystrophy were diagnosed as vulvar dystrophy in gynecological outpatient department of our hospital from 2010 to 2015, and the changes of disease state before and after treatment were recorded. The prevalence rate of 13 870 cases (40.96) in Chengdu area and 6 333 cases (18.70%) in Chengdu area was significantly higher than that in other areas, and 22 998 cases (67.92%) in urban areas were significantly more than 10 861 cases (32.08%) in rural areas) except for the 4050 age group. The prevalence of lichen simplex and lichen sclerosus were significantly different among other age groups (P 0.05). The patients in the two groups were followed up for 6 ~ 12 months after electrophysiological therapy. The color of vulvar skin was improved in 18 cases, the pruritus score was improved in 22 cases (84.62%), the effective rate of bryophyte group was 88.89 cases and that of sclerosing lichen moss group was 50.004 cases, the difference between the two groups was statistically significant (P 0.01). Vulvar malnutrition is relatively common in Sichuan, The patients with simple mosses were younger and had better effect of electrophysiologic therapy.
【作者單位】： 四川大學(xué)華西第二醫(yī)院婦產(chǎn)科;出生缺陷與相關(guān)婦兒疾病教育部重點(diǎn)實(shí)驗(yàn)室(四川大學(xué));
【基金】：四川省學(xué)術(shù)帶頭人培養(yǎng)基金(No.2012DTPY0028,No.2013RST004) 四川省衛(wèi)計(jì)委基金(No.130113) 四川省科技廳科技支撐計(jì)劃項(xiàng)目(No.2014KJT057-2014SZ0001)資助
【分類號(hào)】：R711.72

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