本文關鍵詞： 富于細胞性血管纖維瘤 病理 免疫組化　出處：《中國實用婦科與產科雜志》2015年06期 　論文類型：期刊論文

【摘要】：目的探討外陰富于細胞性血管纖維瘤(CAF)的臨床病理特征、鑒別診斷以及診治方法和預后。方法選擇2014-11-04中國醫(yī)科大學附屬盛京醫(yī)院收治的1例外陰富于細胞性血管纖維瘤的病例,進行臨床特點、組織形態(tài)學、免疫組織化學研究。結合文獻分析本病的臨床表現(xiàn)、病理形態(tài)特點及鑒別診斷。結果富于細胞性血管纖維瘤呈不規(guī)則小葉狀,瘤細胞呈短梭形、大小一致、核卵圓至梭形、核分裂象不易見。腫瘤含大量的小至中等大小的血管,以無分支的毛細血管為主。病理切片特點為疏松排列的梭形細胞、脂肪瘤樣細胞和突出的厚壁血管。免疫組織化學:腫瘤細胞Vimentin陽性,CD34陽性。CD31、SMA、S-100、HMB-45均陰性。結論富于細胞性血管纖維瘤是一種極少見的特殊的外陰部良性軟組織腫瘤,腫瘤可能存在間質細胞增生活性不同的組織學亞型。治療以手術為主,術后需嚴密復查。
[Abstract]:Objective to investigate the clinicopathological features, differential diagnosis, diagnosis and treatment and prognosis of vulvar hemangiofibroma (CAF). Methods one case of cytosolic angiofibroma was selected from Shengjing Hospital affiliated to China Medical University from 2014-11-04. The clinical features, histomorphology and immunohistochemistry were studied. The clinical manifestations, histopathologic features and differential diagnosis of the disease were analyzed. Results Cytoangiofibroma presented irregular lobular shape and short fusiform tumor cells. The tumor contains a large number of small to medium sized blood vessels, mainly non-branched capillaries. The pathological sections are characterized by loosely arranged spindle cells. Immunohistochemistry: tumor cells were Vimentin positive and CD34 positive. CD31 SMAS-100 HMB-45 was negative. Conclusion Cytoangiofibroma is a rare and special benign soft tissue tumor of the vulva. The tumor may have histological subtypes with different stromal cell proliferation activity.
【作者單位】： 中國醫(yī)科大學附屬盛京醫(yī)院婦產科;
【基金】：盛京自由研究者計劃(201303)
【分類號】：R737.3

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本文編號：1554714