本文關鍵詞： 支原體 不孕不育 婦女 藥敏試驗　出處：《中華醫(yī)院感染學雜志》2017年11期 　論文類型：期刊論文

【摘要】：目的探討不孕婦女支原體感染狀況與藥物敏感性研究,為臨床診治提供參考依據(jù)。方法回顧性分析2010年8月-2016年8月醫(yī)院不孕不育�？剖罩蔚牟辉胁挥龐D女925例,提取患者宮頸分泌物進行藥敏試驗,統(tǒng)計患者的支原體感染率及藥敏率和耐藥率。結果 925例不孕婦女中有786例發(fā)生支原體感染,感染率84.97%,其中629例發(fā)生解脲脲支原體(Uu)感染占80.02%,45例發(fā)生人支原體(Mh)感染占5.73%,112例發(fā)生Uu+Mh混合感染占14.25%;786例支原體感染患者年齡多分布在25~30歲占總數(shù)的67.56%,各不同類型支原體感染均多分布在25~30歲,而合并感染中分布36~40歲患者比例明顯增多(P0.05);Uu對交沙霉素最敏感(92.05%),耐藥率最高的是環(huán)丙沙星(67.72%),Mh對壯觀霉素最敏感(86.67%),耐藥率最高的是克拉霉素(93.33%),支原體陽性菌株對抗菌藥物的多藥耐藥顯示,Uu多為4~6種抗菌藥物耐藥比例為63.12%,Mh多藥耐藥多在10種以上達42.22%,合并感染多藥耐藥多在10種抗菌藥物以上比例達51.79%。結論不孕不育婦女支原體感染率較高,尤其是Uu感染,年齡在25~30歲的婦女易感染疾病,對不孕婦女應加強支原體檢測和藥敏試驗,其中交沙霉素、克拉霉素、壯觀霉素和強力霉素可作為支原體感染的首選藥物。
[Abstract]:Objective to study the infection status and drug sensitivity of mycoplasma in infertile women, and to provide reference for clinical diagnosis and treatment. Methods 925 infertile women admitted in hospital from August 2010 to August 2016 were retrospectively analyzed. The mycoplasma infection rate, drug sensitivity rate and drug resistance rate were calculated. Results 786 of 925 infertile women developed mycoplasma infection. The infection rate was 84.97, of which 629 cases had Ureaplasma Urealyticum Ureaplasma Ureaplasma Urealyticum (UUU) infection (80.02%) and 45 cases (45 cases) of Ureaplasma Urealyticum (UU) infection accounted for 5.73% (112 cases) and 112 cases of UU Mh mixed infection (14.25%). 786 cases of mycoplasma infection were mostly distributed in the age of 2530 years and accounted for 67.56% of the total. Most of mycoplasma infection occurred in 2530 years old. However, the proportion of patients aged 36 to 40 years with co-infection increased significantly. P0.05Uu was most sensitive to josamycin and 92.05%. The most sensitive drug resistance rate was ciprofloxacin 67.72 Mh to spectinomycin, and the highest drug resistance rate was clarithromycin 93.3333B. mycoplasma positive strains were antagonistic to spectinomycin, and the most sensitive to spectinomycin was ciprofloxacin 67.72Mh, and the highest drug resistance rate was clarithromycin 93.33B. The multidrug resistance of bacterial drugs showed that the ratio of 6 kinds of antimicrobial drug resistance to UU was 43.12Mh was more than 10, and that of co-infection was 51.79. Conclusion the infection rate of mycoplasma in infertile women is higher than that in infertile women. Especially for UU infection, women aged 25 ~ 30 years are susceptible to infection. Mycoplasma detection and drug sensitivity test should be strengthened in infertile women. Among them, josamycin, clarithromycin, spectinomycin and doxycycline can be used as the first choice for mycoplasma infection.
【作者單位】： 綿陽市中心醫(yī)院婦產(chǎn)科;
【分類號】：R711.6

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