本文關(guān)鍵詞： 產(chǎn)后 盆腔炎 病原菌分布 耐藥性　出處：《中華醫(yī)院感染學(xué)雜志》2017年24期 　論文類型：期刊論文

【摘要】：目的分析產(chǎn)后盆腔炎(PID)患者的病原菌分布特點(diǎn)和耐藥情況的研究,探討產(chǎn)后患者盆腔炎感染特征。方法回顧性選取在2015年3月-2016年7月期間于醫(yī)院婦產(chǎn)科明確診斷為盆腔炎的112例患者為研究對象,采集宮內(nèi)分泌物進(jìn)行菌株培養(yǎng)分離,并采用MicroScan walkAway-96全自動(dòng)微生物菌種鑒定儀進(jìn)行細(xì)菌鑒定和藥敏試驗(yàn),統(tǒng)計(jì)分析PID患者的病原菌鑒定結(jié)果及耐藥性。結(jié)果 112例感染患者送檢的分泌物樣本中共檢出病原菌97株,檢出率為86.61%,其中革蘭陰性菌68株占70.10%,革蘭陽性菌22株占22.68%,真菌7株占7.22%;大腸埃希菌對諾氟沙星、慶大霉素和頭孢替唑鈉的耐藥率較高,均50%,對頭孢克肟和美羅培南的耐藥率較低,均5%;肺炎克雷伯菌對諾氟沙星、慶大霉素和左氧氟沙星耐藥率較高,均≥60%;金黃色葡萄球菌對青霉素、氨芐西林和克林霉素的耐藥率較高,均70%。結(jié)論 PID是產(chǎn)后女性易感染疾病,其主要致病菌為革蘭陰性菌,而美羅培南、頭孢克肟及氟喹諾酮類抗菌藥物對其有明確地抑菌作用,在臨床治療產(chǎn)后盆腔炎患者應(yīng)根據(jù)細(xì)菌培養(yǎng)結(jié)果,能夠合理使用抗菌藥物,有效控制感染發(fā)展和降低耐藥情況的產(chǎn)生。
[Abstract]:Objective to analyze the distribution and drug resistance of pathogenic bacteria in patients with postpartum pelvic inflammatory disease (PIDD). Methods from March 2015 to July 2016, 112 patients diagnosed as pelvic inflammatory disease in hospital gynecology and obstetrics department were selected retrospectively. Intrauterine secretions were collected for strain culture and isolation, and MicroScan walkAway-96 automatic microorganism identification instrument was used to identify bacteria and drug sensitivity test. Results 97 strains of pathogenic bacteria were detected in the secretion samples of 112 patients with PID, and the detection rate was 86.61%. Among them, 68 strains of Gram-negative bacteria accounted for 70.10%, 22 strains of Gram-positive bacteria accounted for 22.68% and 7 strains of fungi accounted for 7.22%. The resistance rate of Escherichia coli to norfloxacin, gentamycin and ceftiazole sodium was higher than that of cefixime and meropenem, and the resistance rate of Escherichia coli to norfloxacin, gentamycin and ceftiazole sodium was higher than that of cefixime and meropenem. The resistance rate of Klebsiella pneumoniae to norfloxacin, gentamicin and levofloxacin was higher than 60%. Staphylococcus aureus was resistant to penicillin, ampicillin and clindamycin, all of which were 70. Conclusion PID is susceptible to infection in postpartum women, and the main pathogenic bacteria are Gram-negative bacteria and meropenem. Cefixime and fluoroquinolones have a definite bacteriostatic effect on them. In clinical treatment of postpartum pelvic inflammatory disease patients should be able to use antibiotics reasonably according to the results of bacterial culture. Effectively control the development of infection and reduce the incidence of drug resistance.
【作者單位】： 濰坊市益都中心醫(yī)院產(chǎn)科;
【基金】：山東省醫(yī)藥衛(wèi)生科技廳科研基金資助項(xiàng)目(2016WS0544)
【分類號】：R711.33
【正文快照】： 盆腔炎(PID)是育齡女性常見的婦科疾病[1],多因女性的盆腔生殖器官及周圍組織發(fā)生炎性反應(yīng),而導(dǎo)致的盆腔腹膜產(chǎn)生炎癥,病癥可見子宮、輸卵管和盆腔結(jié)締組織等單個(gè)部位或者其他多個(gè)部位同時(shí)發(fā)病。根據(jù)臨床統(tǒng)計(jì)[2-3],我國女性盆腔炎的發(fā)病率可達(dá)28%以上,其中發(fā)病人群以產(chǎn)后婦女

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