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  本文關(guān)鍵詞： 三維能量多普勒超聲 子宮頸癌 新輔助化療　出處：《中國超聲醫(yī)學(xué)雜志》2017年07期 　論文類型：期刊論文

【摘要】：目的探討三維能量多普勒超聲在宮頸癌新輔助化療療效評估中的應(yīng)用價(jià)值。方法對25例接受新輔助化療的宮頸癌患者于化療前及化療結(jié)束后2周行三維能量多普勒超聲檢查,應(yīng)用VOCAL功能計(jì)算病灶體積,采用血管形成指數(shù)(VI)、血流指數(shù)(FI)、血管血流指數(shù)(VFI)評估病灶在化療前及化療后的血流灌注情況,隨機(jī)收集35例正常人宮頸作為對照組,比較宮頸癌新輔助化療前后三維能量多普勒超聲檢查結(jié)果的差異。結(jié)果 25例宮頸癌患者在新輔助化療前后和35例正常人宮頸的血流參數(shù)比較差異有統(tǒng)計(jì)學(xué)意義(P0.05)。25例宮頸癌患者中,19例新輔助化療有效,其中2例病灶消失,17例病灶體積較化療前變小;6例化療無效,其中病灶無變化3例,病灶增大3例�；熡行ЫM的化療后VI、FI、VFI較化療前變小(P0.05);化療無效組的化療后VI、FI、VFI較化療前無變化(P0.05)。結(jié)論應(yīng)用三維能量多普勒超聲技術(shù)檢測宮頸癌化療前后腫瘤血流灌注的變化可反映化療療效,為臨床優(yōu)化宮頸癌患者的個(gè)體化的治療方案提供參考意見。
[Abstract]:Objective to evaluate the value of three dimensional power Doppler ultrasound in evaluating the efficacy of neoadjuvant chemotherapy for cervical cancer. Methods 25 patients with cervical cancer receiving neoadjuvant chemotherapy were treated with three dimensional multiple energy before chemotherapy and 2 weeks after chemotherapy. Pleurian ultrasound. VOCAL function was used to calculate the volume of the lesion. The blood flow perfusion was evaluated before and after chemotherapy by using the angiogenesis index (VII), the blood flow index (FII) and the vascular flow index (VFI). 35 cases of normal human cervix were randomly collected as control group. To compare the results of three dimensional power Doppler ultrasonography before and after neoadjuvant chemotherapy for cervical cancer. There were significant differences in blood flow parameters between 25 patients with cervical cancer before and after neoadjuvant chemotherapy and 35 normal controls (. P0.05. 25 cases of cervical cancer. Neoadjuvant chemotherapy was effective in 19 cases, in which 2 lesions disappeared and 17 lesions became smaller than those before chemotherapy. 6 cases had no effect of chemotherapy, 3 cases had no change in focus and 3 cases had enlarged focus. In the effective group, the VFI of VIFI was smaller than that of P0.05 before chemotherapy. VIFI after chemotherapy in the group of ineffective chemotherapy. Conclusion Three-dimensional power Doppler ultrasound can be used to detect the changes of tumor blood perfusion before and after chemotherapy in cervical cancer, which can reflect the effect of chemotherapy. To provide reference for clinical optimization of individualized treatment for cervical cancer patients.
【作者單位】： 中山大學(xué)附屬第三醫(yī)院超聲科;
【基金】：廣東省科技計(jì)劃項(xiàng)目(No.2014A020212486) 廣東省醫(yī)學(xué)科學(xué)技術(shù)研究基金(No.A2015284)
【分類號】：R445.1;R737.33
【正文快照】： 結(jié)果25例宮頸癌患者在新輔助化療前后和35例正常人宮頸的血流參數(shù)比較差異有統(tǒng)計(jì)學(xué)意義(P0.05)。25例宮頸癌患者中,19例新輔助化療有效,其中2例病灶消失,17例病灶體積較化療前變小;6例化療無效,其中病灶無變化3例,病灶增大3例。化療有效組的化療后VI、FI、VFI較化療前變小(P

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