本文關(guān)鍵詞： 妊高癥 硫酸鎂 硝苯地平 療效　出處：《臨床醫(yī)藥文獻(xiàn)電子雜志》2016年44期 　論文類(lèi)型：期刊論文

【摘要】：目的探討硫酸鎂與硝苯地平治療妊高癥的療效。方法選取我院2015年9月~2016年9月婦產(chǎn)科收治的妊高癥患者130例作為研究對(duì)象,隨機(jī)分為對(duì)照組和觀察組,對(duì)照組單用硫酸鎂治療,觀察組采用硫酸鎂與硝苯地平治療,比較兩組患者的療效、血壓及24 h尿蛋白定量、臍動(dòng)脈阻力指數(shù)、紅細(xì)胞比容、血粘度。結(jié)果觀察組和對(duì)照組治療有效率分別為為95.38%和81.54%,兩組患者治療效比較,觀察組明顯較高于對(duì)照組,差異有統(tǒng)計(jì)學(xué)意義(P0.05);治療后觀察組的收縮壓、舒張壓及24 h尿蛋白定量監(jiān)測(cè)結(jié)果均明顯較對(duì)照組改善,差異有統(tǒng)計(jì)學(xué)意義(P0.05);治療后觀察組的臍動(dòng)脈阻力指數(shù)、紅細(xì)胞比容、血粘度等指標(biāo)均明顯優(yōu)于對(duì)照組,差異有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論硫酸鎂與硝苯地平治療妊高癥有確切療效,控制血壓效果強(qiáng),能有效改善妊娠結(jié)局,提高胎兒質(zhì)量。
[Abstract]:Objective to investigate the efficacy of magnesium sulfate and nifedipine in the treatment of pregnancy induced hypertension (PIH). Control group and observation group were randomly divided into control group and observation group. The control group was treated with magnesium sulfate and nifedipine. The curative effect, blood pressure, 24 h urine protein and umbilical artery resistance index were compared between the two groups. Results the effective rates of the observation group and the control group were 95.38% and 81.54, respectively. The curative effect of the observation group was significantly higher than that of the control group. The difference was statistically significant (P 0.05). The results of systolic blood pressure, diastolic blood pressure and 24 h urine protein quantitative monitoring in the observation group were significantly better than those in the control group (P 0.05). After treatment, the indexes of umbilical artery resistance index, erythrocyte volume and blood viscosity in the observation group were significantly better than those in the control group. Conclusion magnesium sulfate and nifedipine are effective in the treatment of pregnancy induced hypertension and can effectively improve pregnancy outcome and fetal quality.
【作者單位】： 湖北省襄陽(yáng)市第三人民醫(yī)院婦產(chǎn)科;
【分類(lèi)號(hào)】：R714.246
【正文快照】： 妊高癥是妊娠期常見(jiàn)疾病,臨床表現(xiàn)為血壓明顯升高,伴有蛋白尿、水腫等,嚴(yán)重時(shí)可引起多系統(tǒng)的功能紊亂,繼發(fā)昏迷、全身肌肉痙攣,甚至發(fā)生產(chǎn)婦心力衰竭及腎衰竭,胎兒發(fā)生早產(chǎn)或死亡,嚴(yán)重威脅母嬰生命安全[1]。因此,臨床對(duì)妊高癥的治療十分重視。本病的發(fā)病機(jī)制尚未明確,臨床缺乏

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