本文關(guān)鍵詞： 奧硝唑 厭氧菌性 盆腔感染 多中心研究 安全性　出處：《中華醫(yī)院感染學雜志》2015年03期 　論文類型：期刊論文

【摘要】：目的探討奧硝唑治療厭氧菌引起的盆腔感染臨床效果及安全性。方法選取2012年4月-2013年11月厭氧菌性盆腔感染患者160例,隨機分為普通組和治療組,每組各80例,普通組使用替硝唑氯化鈉注射液靜脈滴注,每次0.5g,每天兩次,維持治療7d,治療組使用奧硝唑氯化鈉注射液靜脈滴注,用法同普通組,治療后對比兩組患者治療效果、細菌清除率及不良反應(yīng)發(fā)生率。結(jié)果普通組治愈65例,治愈率81.25%,治療組治愈66例,治愈率82.50%,兩組臨床效果相近,差異無統(tǒng)計學意義;細菌清除率普通組為95.35%、治療組為97.22%,兩組臨床效果相近,對比差異無統(tǒng)計學意義;治療后不良反應(yīng)發(fā)生率治療組為3.75%、普通組為27.50%,兩組對比差異有統(tǒng)計學意義(χ2=11.347,P0.05)。結(jié)論針對厭氧菌引起的盆腔感染患者使用奧硝唑氯化鈉注射液治療臨床效果顯著確切,且安全性高,值得臨床推廣應(yīng)用。
[Abstract]:Objective to investigate the efficacy and safety of ornidazole in the treatment of pelvic infection caused by anaerobes. Methods 160 patients with anaerobic-induced pelvic infection from April 2012 to November 2013 were selected. The patients were randomly divided into two groups (80 cases in each group). The common group was treated with tinidazole sodium chloride injection (0.5 g, twice a day) for 7 days. The treatment group was treated with ornidazole sodium chloride injection intravenous drip, and compared with the common group after treatment, the treatment effect, bacterial clearance rate and adverse reaction rate were compared between the two groups. Results 65 cases were cured in the common group. The cure rate was 81.25%, 66 cases were cured in the treatment group, and the cure rate was 82.50%. The clinical effect of the two groups was similar, but the difference was not statistically significant. The bacterial clearance rate was 95.35 in the common group and 97.22 in the treatment group. The clinical effect of the two groups was similar, but the difference was not statistically significant. The incidence of adverse reactions after treatment was 3.75 in the treatment group and 27.50 in the common group. The difference between the two groups was statistically significant (蠂 ~ 2 / 11.347). Conclusion Ornidazole sodium chloride injection is effective and safe in the treatment of pelvic infection caused by anaerobes, which is worth popularizing.
【作者單位】： 無錫市第九人民醫(yī)院婦產(chǎn)科;
【基金】：江蘇省科技廳基金資助項目(JS20120386)
【分類號】：R711.33
【正文快照】： 盆腔感染性疾病是指女性生殖器官以及周圍的結(jié)締組織等部位,發(fā)生由于感染等原因而出現(xiàn)的炎癥現(xiàn)象,可能有急性、慢性盆腔炎,盆腔、輸卵管以及卵巢等部位發(fā)生膿腫現(xiàn)象,厭氧菌性盆腔感染不僅對患者的正常生活造成困擾,還對生殖健康造成影響,可能影響生育能力等[1-2]。目前治療厭

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相關(guān)期刊論文 前3條

1 ;Chemotherapy with laparoscope-assisted continuous circulatory hyperthermic intraperitoneal perfusion for malignant ascites[J];World Journal of Gastroenterology;2010年15期

2 Andrzej Dabrowski;Wojciech Kwasniewski;Tomasz Skoczylas;Wies，

本文編號：1462595