發(fā)布時(shí)間：2018-01-16 18:31

  本文關(guān)鍵詞：人絨毛膜促性腺激素、甲胎蛋白、非結(jié)合雌三醇水平與妊娠期并發(fā)癥及分娩結(jié)局的關(guān)系　出處：《中國(guó)婦幼保健》2016年23期 　論文類(lèi)型：期刊論文

  更多相關(guān)文章： 妊娠 并發(fā)癥 β-hCG AFP uE_

【摘要】：目的分析血清人絨毛膜促性腺激素(β-hCG)、甲胎蛋白(AFP)、非結(jié)合雌三醇(uE_3)水平與妊娠期并發(fā)癥及分娩結(jié)局的關(guān)系。方法以2014年3月-2015年3月在該院進(jìn)行產(chǎn)前檢查,孕中期進(jìn)行血清β-hCG、AFP、uE_3水平檢測(cè),并在該院住院分娩的產(chǎn)婦為觀察對(duì)象,根據(jù)血清β-hCG、AFP、uE_3的MoM值分為正常組、過(guò)高組和降低組。比較β-hCG、AFP、uE_3正常組、升高組和降低組妊娠并發(fā)癥和不良分娩結(jié)局的發(fā)生率。結(jié)果血清AFP水平過(guò)高組發(fā)生妊娠期高血壓、妊娠期糖尿病和胎盤(pán)早剝以及早產(chǎn)的例數(shù)明顯多于正常組,差別具有統(tǒng)計(jì)學(xué)意義(P0.05);血清β-hCG過(guò)高組和uE_3降低組產(chǎn)婦發(fā)生妊娠期高血壓、妊娠期糖尿病和胎盤(pán)早剝的例數(shù)明顯多于正常組,且早產(chǎn)和產(chǎn)后出血的發(fā)生率也較正常組高,差異有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論高水平的β-hCG、AFP和低水平的uE_3與妊娠期并發(fā)癥和不良分娩結(jié)局的發(fā)生密切相關(guān)。
[Abstract]:Objective to analyze serum human chorionic gonadotropin (尾 -hCGN). The relationship between the level of unconjugated estriol uE _ 3 and the complications of pregnancy and the outcome of delivery. Methods Prenatal examination was conducted in the hospital from March 2014 to March 2015. The serum levels of 尾 -hCGCG-AFPnuE3 were measured in the second trimester of pregnancy, and the pregnant women who were delivered in the hospital were observed according to the serum levels of 尾 -hCGCG-AFP. The MoM values of uE_3 were divided into normal group, hypertrophic group and decreased group. Results the incidence of pregnancy complications and poor delivery outcome in the high serum AFP group was significantly higher than that in the control group. Results the hypertension complicating pregnancy was found in the high serum AFP level group. The number of cases of gestational diabetes mellitus, placental abruption and preterm delivery was significantly higher than that of normal group, and the difference was statistically significant (P 0.05). Hypertension complicating pregnancy, gestational diabetes mellitus and placental abruption were more common in the high serum 尾 -hCG group and uE_3 reduction group than in the normal group, and the incidence of premature delivery and postpartum hemorrhage was also higher than that in the normal group. Conclusion the high level of 尾 -hCGN AFP and the low level of uE_3 are closely related to the occurrence of pregnancy complications and poor delivery outcome.
【作者單位】： 南京市婦幼保健院;
【分類(lèi)號(hào)】：R714.2
【正文快照】： 妊娠期由于特殊的生理性改變,血容量的增加、體內(nèi)雌孕激素分泌的增加、生長(zhǎng)抑素等拮抗胰島素受體的激素分泌的增高,均可促進(jìn)妊娠期高血壓、妊娠期糖尿病以及妊娠期合并心臟病的發(fā)生,增加早產(chǎn)、引產(chǎn)以及剖宮產(chǎn)的幾率,并可導(dǎo)致4%~5%左右的胎兒宮內(nèi)生長(zhǎng)發(fā)育窘迫和新生兒缺血缺氧

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