發(fā)布時(shí)間：2018-01-06 15:26

  本文關(guān)鍵詞：晚發(fā)型子癇前期胎盤124例臨床病理分析　出處：《診斷病理學(xué)雜志》2016年12期 　論文類型：期刊論文

  更多相關(guān)文章： 晚發(fā)型子癇前期 胎盤病理 胎兒宮內(nèi)生長(zhǎng)受限 預(yù)后

【摘要】：目的探討124例晚發(fā)型子癇前期胎盤的臨床病理特點(diǎn)及預(yù)后。方法參照子癇前期診斷標(biāo)準(zhǔn)進(jìn)行分類,124例晚發(fā)型子癇前期病例分為輕度組(83例)和重度組(41例),對(duì)2組患者的一般臨床資料、胎盤組織病理特點(diǎn)及圍產(chǎn)結(jié)局進(jìn)行分析、比較。結(jié)果兩組病例中胎盤主要的鏡下改變包括蛻膜血管病變、梗死、胎盤早剝和絨毛發(fā)育不良,其中胎盤絨毛發(fā)育不良的發(fā)生率最高,其次是胎盤梗死。輕度組中輕度蛻膜血管病的發(fā)病率為21.7%(18/83)、重度組中的發(fā)病率為56.1%(23/41),兩組間比較有顯著差異(P0.01)。輕度組中胎盤絨毛發(fā)育不良的發(fā)病率為40.9%(34/83),重度組為70.7%(29/41),兩組間差異顯著(P0.05)。輕度組中胎兒宮內(nèi)生長(zhǎng)受限的發(fā)生率為21.7%(18/83),重度組為41.5%(17/41),兩組間差異顯著(P0.05)。輕度組中胎兒存活率為98.8%(82/83),重度組為92.7%(38/41),兩組間無明顯差異(P0.05)。另外重度蛻膜血管病、胎盤梗死、臍帶異常及合并糖尿病方面兩組比較無明顯差異。結(jié)論晚發(fā)型重度子癇前期組的胎兒宮內(nèi)生長(zhǎng)受限的發(fā)生率高于輕度組。兩組間胎兒存活率無明顯差異,子癇前期預(yù)后不良。晚發(fā)型重度子癇前期的部分圍生結(jié)局差于輕度組。
[Abstract]:Objective to investigate the clinical pathological characteristics and prognosis of 124 cases of late onset preeclampsia. Methods to classify the reference standard in diagnosing pre eclampsia, 124 cases of late onset preeclampsia patients were divided into mild group (83 cases) and severe group (41 cases), the clinical data of 2 patients, pathological features of placenta and perinatal the outcome of analysis, comparison. Results two cases of placenta main pathological changes including decidual vasculopathy, infarction, placental abruption and villous dysplasia, which placental dysplasia was the highest, followed by placental infarction. Mild group in incidence of mild decidual vascular disease rate was 21.7% (18/83), the incidence of in the severe group was 56.1% (23/41), there was a significant difference between the two groups (P0.01). The mild group of placental dysplasia incidence was 40.9% (34/83), severe group was 70.7% (29/41), the difference between the two groups was significant (P0.05) in the mild group. Intrauterine growth restriction incidence rate was 21.7% (18/83), severe group was 41.5% (17/41), the difference between the two groups was significant (P0.05). In the group of mild fetal survival rate was 98.8% (82/83), severe group was 92.7% (38/41), no significant difference between the two groups (P0.05). In addition, severe ghost film vascular disease, placental infarction, aspects of umbilical cord abnormalities and two with diabetes group had no significant difference. Conclusion late onset severe preeclampsia group intrauterine growth retardation was higher than mild group. Two groups of fetal survival rate had no significant difference in preeclampsia prognosis. Late onset severe preeclampsia part of poor perinatal outcome in the mild group.

【作者單位】： 海淀區(qū)婦幼保健院病理科;北京大學(xué)人民醫(yī)院病理科;海淀區(qū)婦幼保健院產(chǎn)科;
【基金】：北京市海淀區(qū)科技項(xiàng)目(NO:S2013009)
【分類號(hào)】：R714.244
【正文快照】： 子癇前期(preeclampsia,PE)是一種妊娠期特有疾病,以高血壓和蛋白尿?yàn)橹饕R床表現(xiàn),威脅母兒健康,常伴發(fā)較高的孕產(chǎn)婦和圍產(chǎn)兒病死率。對(duì)子癇前期的研究一直為產(chǎn)科領(lǐng)域所矚目,且以往的關(guān)注熱點(diǎn)多集中于子癇前期的病因、發(fā)病機(jī)制及治療等方面,罕有關(guān)于其胎盤組織病理學(xué)特點(diǎn)等方

【相似文獻(xiàn)】

相關(guān)期刊論文 前10條

1 桑翠琴;張震宇;王淑珍;劉浩;郭淑麗;;重度子癇前期/子癇合并急性呼吸窘迫綜合征的診斷與處理[J];中國(guó)醫(yī)刊;2006年10期

2 趙桂花;;重度子癇前期與子癇82例臨床分析[J];臨床醫(yī)藥實(shí)踐雜志;2007年01期

3 楊小頎;嚴(yán)妮子;;子癇前期與血鈣水平相關(guān)性研究[J];實(shí)用臨床醫(yī)學(xué);2007年04期

4 楊小頎;嚴(yán)妮子;;子癇前期與血鈣水平相關(guān)性研究[J];四川生理科學(xué)雜志;2007年01期

5 陳茜;王澤華;;子癇前期的預(yù)測(cè)及預(yù)防[J];華中醫(yī)學(xué)雜志;2007年03期

6 朱倩;;對(duì)38例子癇前期(重)、子癇治愈的體會(huì)[J];實(shí)用預(yù)防醫(yī)學(xué);2007年05期

7 梁英;周麗麗;甘娟;姜碧洋;楊承東;;重度子癇前期在產(chǎn)科ICU監(jiān)護(hù)救治的臨床分析[J];中國(guó)婦幼保健;2008年19期

8 詹衛(wèi)星;鄭九生;;血管緊張素轉(zhuǎn)換酶基因多態(tài)性與重度子癇前期及腎功能損害的關(guān)系[J];江西醫(yī)藥;2008年08期

9 蔡穎;尹國(guó)武;姜鋒;李怡;閔保華;王s，

本文編號(hào)：1388454