妊娠早期血漿同型半胱氨酸水平與早產的關系研究
發(fā)布時間:2018-01-03 22:36
本文關鍵詞:妊娠早期血漿同型半胱氨酸水平與早產的關系研究 出處:《吉林醫(yī)學》2016年12期 論文類型:期刊論文
【摘要】:目的:探討孕早期同型半胱氨酸(Hcy)水平與早產的關系,為早產的預防提供理論依據。方法:以179例早產和足月產孕婦為研究對象,在孕早期測量孕婦同型半胱氨水平,分析孕早期Hcy水平與早產的關系。結果:早產組Hcy水平為(7.81±3.12)μmol/L,足月產組孕早期Hcy水平為(6.73±2.65)μmol/L,足月產組孕早期Hcy水平顯著低于早產組,差異有顯著性統(tǒng)計學意義(t=2.536,P=0.013)。以孕早期Hcy水平7.53μmol/L作為高水平,以Hcy水平≤7.53μmol/L作為低水平組,OR=2.04(95%CI=1.18~3.54);調整葉酸補充、年齡、孕次和產次后OR=1.76(95%CI=1.24~2.28)。結論:孕早期高水平同型半胱氨酸是早產風險的影響因素,可早期進行監(jiān)測預防早產。
[Abstract]:Objective: to investigate the relationship between the level of homocysteine cysteine in early pregnancy and preterm delivery, and to provide theoretical basis for the prevention of premature delivery. Methods: 179 pregnant women with preterm and term delivery were studied. The level of homotypic cysteamine was measured in early pregnancy, and the relationship between the level of Hcy and preterm delivery was analyzed. Results: the Hcy level of premature delivery group was 7.81 鹵3.12 渭 mol/L. The level of Hcy was 6.73 鹵2.65 渭 mol / L in term delivery group, and the level of Hcy in term birth group was significantly lower than that in preterm delivery group. The difference was statistically significant (P < 0.05). The level of Hcy in early pregnancy was 7.53 渭 mol/L. The Hcy level 鈮,
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