本文關(guān)鍵詞：基礎(chǔ)竇卵泡數(shù)預(yù)測IVF患者臨床妊娠結(jié)局的Meta分析　出處：《醫(yī)學(xué)研究雜志》2016年09期 　論文類型：期刊論文

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【摘要】：目的通過Meta分析探討基礎(chǔ)竇卵泡數(shù)預(yù)測IVF妊娠結(jié)局的臨床應(yīng)價值。方法收集國內(nèi)外有關(guān)基礎(chǔ)竇卵泡數(shù)與IVF-ET臨床妊娠結(jié)局的相關(guān)研究,符合納入與排除標(biāo)準(zhǔn)的相關(guān)文獻共11篇,采用Rev Man5.2軟件對納入的文獻進行Meta分析。結(jié)果通過對納入的11項研究進行Meta分析顯示,基礎(chǔ)竇卵泡數(shù)越多,獲卵數(shù)、臨床妊娠率、繼續(xù)妊娠率、種植率越高,差異有統(tǒng)計學(xué)意義。獲卵數(shù)(SMD合并=-0.87,95%CI:-1.22~-0.52;Z=4.84,P=0.000),臨床妊娠率(OR合并=0.62,95%CI:0.54~0.72,Z=6.19,P=0.000)繼續(xù)妊娠率(OR合并=0.21,95%CI:0.08~0.59,Z=3.00,P=0.003);種植率(OR合并=0.59,95%CI:0.49~0.72,Z=5.31,P=0.000),結(jié)果表明,基礎(chǔ)竇卵泡數(shù)越多,獲卵數(shù)和臨床妊娠率就越高。結(jié)論基礎(chǔ)竇卵泡數(shù)可能是體外受精前量化卵巢儲備功能的有利檢測指標(biāo),并直接影響臨床妊娠結(jié)局。
[Abstract]:Objective to explore the clinical value of predicting the outcome of IVF pregnancy by analyzing the number of basal sinus follicles by Meta analysis. Methods a total of 11 related literatures on the number of basal sinus follicles and IVF-ET clinical pregnancy outcomes were collected. There were a total of 11 articles that met the inclusion and exclusion criteria. Rev Man5.2 software was used to conduct the Meta analysis of the included literatures. Results Meta analysis of 11 studies showed that the higher the number of follicles in basal sinus, the higher the number of ovum, clinical pregnancy rate, continuing pregnancy rate and implantation rate. The number of oocytes (SMD and =-0.87,95%CI:-1.22~-0.52; Z=4.84, P=0.000), the clinical pregnancy rate (OR and =0.62,95%CI:0.54~0.72, Z=6.19, P=0.000) on pregnancy rate (OR and =0.21,95%CI:0.08~0.59, Z=3.00, P=0.003); implantation rate (OR and =0.59,95%CI:0.49~0.72, Z=5.31, P=0.000). The results show that the number of antral follicle number, the number of oocytes and clinical the pregnancy rate is higher. Conclusion the number of basal sinus follicles may be a favorable indicator for quantifying ovarian reserve before in vitro fertilization and directly affects the outcome of clinical pregnancy.
【作者單位】： 中國武警總醫(yī)院婦產(chǎn)科;
【分類號】：R714.8
【正文快照】： 自1978年英國劍橋的Steptoe和Edwards教授合作,應(yīng)用體外受精-胚胎移植技術(shù)孕育的世界第1例試管嬰兒Louis Brown誕生,輔助生殖技術(shù)技術(shù)已經(jīng)成為不孕不育的主要治療手段[1]。但是近10~20年來,ART技術(shù)的成功率并沒有大的突破,宮腔內(nèi)人工授精(IUI)的妊娠率為7.4%~12.6%,而IVF/ICSI，

本文編號：1344672