本文關鍵詞：基礎竇卵泡數(shù)預測IVF患者臨床妊娠結局的Meta分析　出處：《醫(yī)學研究雜志》2016年09期 　論文類型：期刊論文

  更多相關文章： 基礎竇卵泡數(shù) 妊娠結局 Meta分析

【摘要】：目的通過Meta分析探討基礎竇卵泡數(shù)預測IVF妊娠結局的臨床應價值。方法收集國內外有關基礎竇卵泡數(shù)與IVF-ET臨床妊娠結局的相關研究,符合納入與排除標準的相關文獻共11篇,采用Rev Man5.2軟件對納入的文獻進行Meta分析。結果通過對納入的11項研究進行Meta分析顯示,基礎竇卵泡數(shù)越多,獲卵數(shù)、臨床妊娠率、繼續(xù)妊娠率、種植率越高,差異有統(tǒng)計學意義。獲卵數(shù)(SMD合并=-0.87,95%CI:-1.22~-0.52;Z=4.84,P=0.000),臨床妊娠率(OR合并=0.62,95%CI:0.54~0.72,Z=6.19,P=0.000)繼續(xù)妊娠率(OR合并=0.21,95%CI:0.08~0.59,Z=3.00,P=0.003);種植率(OR合并=0.59,95%CI:0.49~0.72,Z=5.31,P=0.000),結果表明,基礎竇卵泡數(shù)越多,獲卵數(shù)和臨床妊娠率就越高。結論基礎竇卵泡數(shù)可能是體外受精前量化卵巢儲備功能的有利檢測指標,并直接影響臨床妊娠結局。
[Abstract]:Objective to explore the clinical value of predicting the outcome of IVF pregnancy by analyzing the number of basal sinus follicles by Meta analysis. Methods a total of 11 related literatures on the number of basal sinus follicles and IVF-ET clinical pregnancy outcomes were collected. There were a total of 11 articles that met the inclusion and exclusion criteria. Rev Man5.2 software was used to conduct the Meta analysis of the included literatures. Results Meta analysis of 11 studies showed that the higher the number of follicles in basal sinus, the higher the number of ovum, clinical pregnancy rate, continuing pregnancy rate and implantation rate. The number of oocytes (SMD and =-0.87,95%CI:-1.22~-0.52; Z=4.84, P=0.000), the clinical pregnancy rate (OR and =0.62,95%CI:0.54~0.72, Z=6.19, P=0.000) on pregnancy rate (OR and =0.21,95%CI:0.08~0.59, Z=3.00, P=0.003); implantation rate (OR and =0.59,95%CI:0.49~0.72, Z=5.31, P=0.000). The results show that the number of antral follicle number, the number of oocytes and clinical the pregnancy rate is higher. Conclusion the number of basal sinus follicles may be a favorable indicator for quantifying ovarian reserve before in vitro fertilization and directly affects the outcome of clinical pregnancy.
【作者單位】： 中國武警總醫(yī)院婦產科;
【分類號】：R714.8
【正文快照】： 自1978年英國劍橋的Steptoe和Edwards教授合作,應用體外受精-胚胎移植技術孕育的世界第1例試管嬰兒Louis Brown誕生,輔助生殖技術技術已經成為不孕不育的主要治療手段[1]。但是近10~20年來,ART技術的成功率并沒有大的突破,宮腔內人工授精(IUI)的妊娠率為7.4%~12.6%,而IVF/ICSI，

本文編號：1344672