發(fā)布時間：2018-03-11 14:03

  本文選題：磁共振　切入點(diǎn)：SSFP序列　出處：《川北醫(yī)學(xué)院》2017年碩士論文　論文類型：學(xué)位論文

【摘要】：目的:本研究采用3.0 T MR SSFP序列對健康人群(漢族)左心室相關(guān)指標(biāo)進(jìn)行測量,評價相關(guān)技術(shù)的可行性,提出相應(yīng)不同年齡段、不同性別健康人群(漢族)的參考值范圍,并分析導(dǎo)致左心室相關(guān)指標(biāo)變化的影響因素,為臨床實(shí)踐、科學(xué)研究提供依據(jù)。方法:100名志愿者于川北醫(yī)學(xué)院附屬醫(yī)院行磁共振掃描,通過后處理軟件獲得左心室舒張末期容積(end-diastolic volume,EDV)、收縮末期容積(end-systolic volume,ESV)、每搏輸出量(stroke volume,SV)、心肌質(zhì)量(myocardial mass,MM)、射血分?jǐn)?shù)(ejection fraction,EF)、心輸出量(cardiac output,CO),并以體表面積對EDV、ESV、SV、進(jìn)行標(biāo)化,結(jié)果以均數(shù)±標(biāo)準(zhǔn)差(SX?)的形式表示,并分析上述結(jié)果與性別、年齡和體表面積的關(guān)系。結(jié)果:不同性別之間左心室EDV、ESV、SV、MM、EF、CO存在明顯差異。男性和女性EDV分別為(126±13)ml,(111±14)ml(P0.001);ESV分別為(45±5)ml,(37±4)ml(P0.001);SV分別為(81±9)ml,(74±12)ml(P=0.002);MM分別為(93±13)g,(68±8)g(P0.001);EF分別為(64±2)%,(67±3)%(P0.001);CO分別為(6±1)L/min,(5±1)L/min(P0.05)。男性左心室EDV、ESV、SV、MM、CO明顯大于女性;男性左心室EF小于女性;左心室EDVi、SVi無性別差異;男性左心室ESVi、大于女性。測量結(jié)果通過體表面積(body surface area,BSA)標(biāo)化處理后,男性和女性EDVi分別為(75±6)ml/m2,(72±7)ml/m2(P0.05);SVi分別為(48±5)ml/m2,(48±6)ml/m2(P0.05);ESVi分別為(27±2)ml/m2,(24±2)ml/m2(P0.001)。左心室EDV、EDVi、ESV、ESVi、SV、SVi與年齡呈負(fù)相關(guān),相關(guān)系數(shù)分別為(r=-0.6,P0.001)、(r=-0.6,P0.001)、(r=-0.4,P0.001)、(r=-0.4,P0.001)、(r=-0.6,P0.001)、(r=-0.6,P0.001)。左心室EDV、ESV、SV、CO及MM與BSA呈正相關(guān),相關(guān)系數(shù)分別為(r=0.8,P0.001)、(r=0.8,P0.001)、(r=0.7,P0.001)、(r=0.7,P0.001)、(r=0.9,P0.001)。結(jié)論:1、3.0T MR可提供健康志愿者左心室容積和收縮功能等信息。2、男性左心室EDV、ESV、SV、MM、CO明顯大于女性;男性左心室EF小于女性;左心室EDVi、SVi無性別差異;男性左心室ESV大于女性。3、左心室EDV、EDVi、ESV、ESVi、SV、SVi與年齡呈負(fù)相關(guān)。4、左心室EDV、ESV、SV、CO及MM與BSA呈正相關(guān)。
[Abstract]:Objective: to evaluate the feasibility of the relevant techniques by using 3. 0T Mr SSFP sequence to measure the left ventricular parameters in healthy people (Han), and to propose the range of reference values for different age groups and different genders of healthy people (Han). The factors influencing the changes of left ventricular indexes were analyzed to provide evidence for clinical practice and scientific research. Methods 100 volunteers were scanned by magnetic resonance imaging (MRI) in the affiliated hospital of North Sichuan Medical College. Left ventricular end-diastolic volume volume (EDV), end-systolic volume volume (ESVV), stroke volume volume (SVV), myocardial mass (MMM), ejection fraction (ejection fraction), cardiac output (cardiac output) and cardiac output (cardiac output) were obtained by post-processing software. And analyze the above results and gender, Age and body surface area. Results: there were significant differences between the sexes in left ventricular EDVV / ESVV / MMEF, and the EDV of male and female were 126 鹵13ml / 111 鹵14ml / ml P 0.001 / V = 45 鹵5ml / min respectively, respectively, and the SV was 81 鹵9ml / 774 鹵12ml / min respectively. The left ventricular EVV / P0.002MM / EF was 64 鹵2mg / min, respectively, and 67 鹵367 鹵31mm / min, respectively. The SV6 鹵1L / min of SV6 鹵1L / min was higher than that of male / female's left ventricular echolyma; and the difference between male and female was greater than that of male's ventricular ectasia respectively (P < 0. 001 / min, P < 0. 001), and that of male / female was significantly higher than that of male / female (P < 0. 001L / min), and that of male / female was significantly higher than that of male / female (n = 6 鹵1 / min), and that of male / female was significantly higher than that of male / female (P = 0. 001 / min), and that of male / female was higher than that of male / female / female / female / female. The EF of left ventricle in male was lower than that in female, there was no gender difference in left ventricular EDVV SVi, and that in male was greater than that in female. The EDVi of male and female were 75 鹵6ml / m2ng / 72 鹵7nml / m2p0.05Vi = 48 鹵5ml / m2m2n = 48 鹵5ml / m2P 0.05Vi = 27 鹵2ml / m2p0.05Vi = 27 鹵2mlm224 鹵2ml / m2P0.001respectively. The left ventricular EDVV / ESVVV / E / E / E / E / V / V / I was positively correlated with age, respectively, and the correlation coefficient was 0. 00r-0. 6p 0. 001M and 0. 00r-0. 4p0. 4P0. 4P0. 01P0. 6r-0. 6P0. 1 BSA and 0. 00r-0. 6P0. 1 / 0. 1 BSA, respectively. The correlation coefficient was 0. 00r-0. 6p0. 00r-0. 00r-0. 4P0. 4P0. The correlation coefficients were 0.8T (0.8T) and 0.8g (P 0.001C) respectively. Conclusion: the ratio of left ventricular volume and contractile function in healthy volunteers can be increased by 0.7T Mr, and the EF of left ventricle is smaller in males than in females, and there is no difference between male and female in left ventricular EDV VSVSVSVSVMMMCO. Conclusion there is no significant difference in left ventricular volume and contractile function between male and female, and there is no significant difference between male and female in left ventricular EDVV SVV SVMCO, and there is no significant difference in left ventricular EDV SVT between male and female. The correlation coefficients are as follows: (1) there is no significant difference in left ventricular volume (LVV) and contractile function (LVV) between male and female. The ESV of left ventricle in male was higher than that in female. There was a negative correlation between SVI and age. There was a positive correlation between SVCO and MM and BSA in left ventricular EDV.
【學(xué)位授予單位】：川北醫(yī)學(xué)院
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：R445.2;R540.4

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