產(chǎn)前腎上腺皮質(zhì)激素和產(chǎn)后肺泡表面活性物質(zhì)治療新生兒呼吸窘迫綜合癥的對(duì)比性研究
發(fā)布時(shí)間:2021-01-02 05:26
背景和目的:早產(chǎn)兒呼吸窘迫綜合癥(RDS)是由于缺乏肺泡表面活性物質(zhì)而引起的肺順應(yīng)性降低和呼吸做功增加的呼吸系統(tǒng)疾病。盡管目前圍產(chǎn)期治療技術(shù)有所提高,但此病仍然是新生兒重癥監(jiān)護(hù)病房中新生兒死亡的主要原因。近來,臨床上一些預(yù)防治療新技術(shù)的應(yīng)用明顯提高了此病患兒的存活率。主要措施包括:一是對(duì)有早產(chǎn)高危因素的孕母在產(chǎn)前應(yīng)用腎上腺皮質(zhì)激素,從而促進(jìn)胎兒肺成熟;二是產(chǎn)后給予有適應(yīng)癥的新生兒應(yīng)用外源性肺泡表面活性物質(zhì)以減少肺泡表面張力。大量臨床研究證實(shí),此兩種措施對(duì)預(yù)防和治療早產(chǎn)兒呼吸窘迫綜合癥均有明顯療效,且前者對(duì)后者有協(xié)同作用。本研究旨在評(píng)價(jià)兩種措施聯(lián)合應(yīng)用治療早產(chǎn)兒呼吸窘迫綜合癥的臨床療效是否優(yōu)于任何單一治療措施。方法和材料:對(duì)我院NICU在2003年1月~2007年1月收治的143例RDS患兒進(jìn)行回顧性研究,分組如下:第1組,采用兩種治療措施聯(lián)合治療的患兒(36例);第2組,產(chǎn)前孕母應(yīng)用腎上腺皮質(zhì)激素而產(chǎn)后未應(yīng)用外源性肺泡表面活性物質(zhì)患兒(33例);第3組,產(chǎn)后應(yīng)用外源性肺泡表面活性物質(zhì)而產(chǎn)前孕母未應(yīng)用腎上腺皮質(zhì)激素患兒(39例);第4組,兩種措施均未應(yīng)用的患兒(35例)。觀察分析四組患兒...
【文章來源】:鄭州大學(xué)河南省 211工程院校
【文章頁數(shù)】:76 頁
【學(xué)位級(jí)別】:碩士
【文章目錄】:
摘要
Abstract
Ⅰ.A comparative study on the role of antenatal corticosteroids and postnatal surfactant in Respiratory Distress Syndrome:the combined versus individual therapy
1.Introduction
2.Aims and objectives
3.Materials and methods
4.Observations and results
5.Discussion
6.Conclusions
7.References
Ⅱ.A comparative study on the role of antenatal corticosteroids and postnatal surfactant in Respiratory Distress Syndrome:the combined versus individual therapy and review of the literature
8 Study background of RDS
9 Incidence and Statistics by country
10 Etiology and Risk factors
11 Pathophysiology and Pathology
12 Clinical manifestations
13 Diagnosis
14 Differential Diagnosis
15 Prevention and Treatment
16 Complications and Prognosis
17 Review of the literature
18 References
Abbreviations
Acknowledgement
本文編號(hào):2952744
【文章來源】:鄭州大學(xué)河南省 211工程院校
【文章頁數(shù)】:76 頁
【學(xué)位級(jí)別】:碩士
【文章目錄】:
摘要
Abstract
Ⅰ.A comparative study on the role of antenatal corticosteroids and postnatal surfactant in Respiratory Distress Syndrome:the combined versus individual therapy
1.Introduction
2.Aims and objectives
3.Materials and methods
4.Observations and results
5.Discussion
6.Conclusions
7.References
Ⅱ.A comparative study on the role of antenatal corticosteroids and postnatal surfactant in Respiratory Distress Syndrome:the combined versus individual therapy and review of the literature
8 Study background of RDS
9 Incidence and Statistics by country
10 Etiology and Risk factors
11 Pathophysiology and Pathology
12 Clinical manifestations
13 Diagnosis
14 Differential Diagnosis
15 Prevention and Treatment
16 Complications and Prognosis
17 Review of the literature
18 References
Abbreviations
Acknowledgement
本文編號(hào):2952744
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