【摘要】：目的和意義：觀察刺四縫及調(diào)脾合劑治療小兒厭食癥脾運(yùn)失健證的臨床療效。通過臨床研究獲得外治法結(jié)合口服中成藥比單純用口服中成藥治療小兒厭食癥的優(yōu)越性,進(jìn)一步豐富治療小兒厭食癥的內(nèi)容,為臨床常見、影響兒童健康的小兒厭食癥研究出有效、安全、便于推廣應(yīng)用的中醫(yī)治療方法。 研究方法：所有病例來自江蘇省中醫(yī)院兒科門診,采用隨機(jī)對照試驗(yàn)設(shè)計法,將受試病例按1：1比例隨機(jī)分為試驗(yàn)組和對照組(試驗(yàn)組30例,對照組30例),試驗(yàn)組采用調(diào)脾合劑聯(lián)合刺四縫治療：調(diào)脾合劑(蒼術(shù)280g,佩蘭280g,陳皮128g,炙內(nèi)金128g,炒山楂280g,蔗糖80g)口服,刺四縫是用三棱針刺入患兒雙手四縫約1分深,擠出淡黃色液體；對照組單純采用調(diào)脾合劑口服治療。調(diào)脾合劑用量用法為小于1歲兒童每次5mL,1～3歲兒童每次10mL,3～6歲兒童每次15mL,大于6歲兒童每次20mL,均每日3次,口服,2周為1個療程,治療2個療程。刺四縫用法為1周點(diǎn)刺1次,2周為1個療程,治療2個療程。 結(jié)果：治療組痊愈14例,占46.7%,顯效8例,占26.7%,進(jìn)步5例,占16.6%,無效3例,占10.0%,總有效率90.0%；對照組痊愈7例,占23.3%,顯效7例,占23.3%,進(jìn)步3例,占10.0%,無效13例,占43.4%,總有效率56.6%；兩組比較,在總體療效上,P0.05,差異有統(tǒng)計學(xué)意義；兩組治療后患兒血紅蛋白及微量元素鋅變化量比較,差異有顯著統(tǒng)計學(xué)意義(P0.05),治療組在主癥即改善食欲、食量程度上均優(yōu)于對照組,在次癥即面色、形體消瘦程度、舌象、脈象等方面改善程度上亦優(yōu)于對照組,說明治療組對小兒厭食癥治療的臨床療效均優(yōu)于對照組。另外兩組患兒治療期間均沒有出現(xiàn)嚴(yán)重不良反應(yīng)。 結(jié)論：通過臨床研究,外治法聯(lián)合口服中成藥治療組的療效明顯優(yōu)于單純口服中成藥對照組,有顯著統(tǒng)計學(xué)意義(P0.05)。而且針刺四縫穴方法日益體現(xiàn)出其祖國醫(yī)學(xué)的優(yōu)勢,簡單、易于操作、療效肯定,方便推廣。
[Abstract]:Objective and significance: to observe the clinical effect of Siniao and Tiaopi mixture in treating children anorexia. The advantages of external therapy combined with oral Chinese patent medicine in the treatment of infantile anorexia were obtained through clinical research. It is common in clinic to enrich the content of treatment of infantile anorexia. Infantile anorexia, which affects children's health, has developed effective, safe and convenient traditional Chinese medicine (TCM) treatment. Methods: all the cases came from the pediatric outpatient department of Jiangsu Provincial traditional Chinese Medicine Hospital. The patients were randomly divided into the trial group (30 cases in the experimental group, 30 cases in the control group) and the control group (30 cases in the control group) according to the 1:1 ratio. The experimental group was treated with Tiaopi mixture combined with four seams: Tiaopi mixture (280g Atractylodes, 280g Perrin, 128g Chen Pei, 128g broiled Hawthorn, 280g sucrose). Extrusion of yellowish liquid; The control group was treated with Tiaopi mixture orally. The dosage of Tiaopi mixture was as follows: the dosage of Tiaopi mixture was 15 mL / time in children aged less than 1 year old and 20 mL / time in children aged 10 mL / 3 and 20 mL / time in children aged less than 6 years. The dosage of Tiaopi mixture was taken orally, 2 weeks as a course of treatment for 2 courses of treatment. Four seams were used as 1 week prick, 2 weeks as a course of treatment, 2 courses of treatment. Results: in the treatment group, 14 cases were cured (46.7%), 8 cases (26.7%) were markedly effective, 5 cases (16.6%) were improved, 3 cases (10.0%) were ineffective, and the total effective rate was 90.0%. In the control group, 7 cases were cured (23. 3%), 7 cases were markedly effective (23. 3%), 3 cases were improved, 13 cases were ineffective, 13 cases were ineffective, and the total effective rate was 56. 6%. Compared with the two groups, the overall curative effect, P0.05, the difference was statistically significant; The changes of hemoglobin and trace element zinc in the two groups were significantly different after treatment (P0.05). In the treatment group, the appetite was improved and the amount of food was better than that in the control group. The improvement of tongue and pulse was better than that of the control group, which indicated that the treatment group was superior to the control group in the treatment of infantile anorexia. In the other two groups, there was no serious adverse reaction during the treatment. Conclusion: through the clinical research, the curative effect of external treatment combined with oral Chinese patent medicine treatment group is obviously better than that of the simple oral Chinese patent medicine control group, which has significant statistical significance (P0.05). And the method of acupuncture on Sijiao points is more and more superior in traditional Chinese medicine, which is simple, easy to operate, effective and easy to popularize.
【學(xué)位授予單位】：南京中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2012
【分類號】：R272

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