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反復(fù)呼吸道感染患兒中醫(yī)體質(zhì)與微量元素關(guān)系的探討

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【摘要】:目的:通過對反復(fù)呼吸道感染患兒進(jìn)行體質(zhì)分型,測定血中微量元素,探討反復(fù)呼吸道感染患兒中醫(yī)體質(zhì)類型與微量元素的關(guān)系。 材料與方法:選取遼寧中醫(yī)藥大學(xué)附屬醫(yī)院2011年3月 2011年9月兒科門診RRTI患兒共計31例,進(jìn)行體質(zhì)分型,以原子吸收分光光度法測定血中微量元素(鈣、鐵、鋅、銅、鉛、錳、鉻)含量,并與同期納入的12例正常兒童進(jìn)行對比。數(shù)據(jù)資料采用SPSS17.0軟件進(jìn)行統(tǒng)計學(xué)分析處理。 結(jié)果: 1. RRTI組31例復(fù)感兒符合單一質(zhì)者16例(51.61%),其中氣虛質(zhì)8例(25.81%),,陰虛質(zhì)5例(16.13%),痰濕質(zhì)2例(6.45%);復(fù)合質(zhì)15例(48.39%),均為氣陰兩虛質(zhì)。 2. RRTI組中鈣、鐵、鋅、銅均值較對照組減低,其中鐵、鋅兩組比較有顯著性差異P<0.01;鉛、錳、鉻均值較對照組增高,其中鉛升高有顯著性差異P<0.01,鉻升高有統(tǒng)計學(xué)意義P<0.05。 3.單一質(zhì)和復(fù)合質(zhì)中鋅、鐵、鉛含量分別與對照組有顯著性差異,復(fù)合質(zhì)中錳元素與對照組有統(tǒng)計差異P<0.05,鈣元素在單一質(zhì)與復(fù)合質(zhì)間比較有統(tǒng)計差異P<0.05,但與對照組無統(tǒng)計差異。 4. RRTI組患兒中,鉛含量在80μg/L以上,單一質(zhì)與復(fù)合質(zhì)鉛超標(biāo)(>100μg/L)分別為4例、9例,占自身25%、60%。兩種體質(zhì)鉛超標(biāo)比為1:2.4。 結(jié)論: 1.RRTI患兒中醫(yī)體質(zhì)類型分布不均勻,氣陰兩虛質(zhì)最多(48.39%),其次為氣虛質(zhì)(25.81%),但單一體質(zhì)與復(fù)合體質(zhì)分布未見明顯差異。 2.RRTI患兒血中微量元素含量存在紊亂,鐵、鋅減低及鉛、鉻升高與對照組相比均有統(tǒng)計意義。 3.單一質(zhì)與復(fù)合質(zhì)對比,除鈣元素外均無統(tǒng)計學(xué)差異,復(fù)合質(zhì)中錳元素比對照組升高有統(tǒng)計意義。 4.RRTI患兒鉛含量偏高,超標(biāo)(>100μg/L)嚴(yán)重,31例患兒中有13例(41.94%)超標(biāo),復(fù)合質(zhì)明顯多于單一質(zhì)(2.4:1)。
[Abstract]:Objective: to study the relationship between TCM constitution type and trace elements in children with recurrent respiratory tract infection by determining trace elements in blood. Materials and methods: 31 pediatric outpatients with RRTI were selected from the affiliated Hospital of Liaoning University of traditional Chinese Medicine from March 2011 to September 2011 to type their constitution. The trace elements (Ca, Fe, Zn, Cu, Pb, mn) in blood were determined by atomic absorption spectrophotometry (AAS). Chromium content was compared with 12 normal children in the same period. The data were analyzed by SPSS17.0 software. Results: 1. In RRTI group, 16 cases (51.61%) were conformed to single substance, including 8 cases (25.81%) of deficiency of qi, 5 cases (16.13%) of yin deficiency, 2 cases (6.45%) of phlegm dampness. 15 cases (48.39%) of compound substance were both deficiency of Qi and Yin. 2. The mean values of calcium, iron, zinc and copper in RRTI group were significantly lower than those in control group (P < 0.01). The levels of lead, manganese and chromium were significantly higher than those of the control group (P < 0.01), and the increase of chromium was statistically significant (P < 0.05). 3. The contents of Zn, Fe and Pb in single and compound materials were significantly different from those in control group, but there were statistical differences in mn and Ca between the two groups (P < 0.05). But there was no statistical difference between the control group and the control group. 4. In the RRTI group, the lead content was over 80 渭 g / L, and there were 4 cases (> 100 渭 g / L) of single and compound lead (> 100 渭 g / L), 9 cases (25 渭 g / L). The lead ratio of two kinds of constitution is 1: 2.4. Conclusion: the distribution of TCM constitution in 1.RRTI children is not uniform, the deficiency of Qi and Yin is the most (48.39%), the second is deficiency of Qi (25.81%), but there is no significant difference between single constitution and compound constitution. The levels of trace elements in blood of children with 2.RRTI were disturbed. The decrease of iron and zinc and the increase of lead and chromium had statistical significance compared with the control group. 3. There was no statistical difference between the single substance and the compound substance except calcium. Manganese in the compound was significantly higher than that in the control group. The lead content of 4.RRTI patients was higher than 100 渭 g / L (> 100 渭 g / L). 13 out of 31 cases (41.94%) were in excess of the standard, and the compound substance was obviously more than the single one (2.4: 1).
【學(xué)位授予單位】:遼寧中醫(yī)藥大學(xué)
【學(xué)位級別】:碩士
【學(xué)位授予年份】:2012
【分類號】:R272

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