【摘要】：目的探討輕度胃腸炎并良性嬰幼兒驚厥的病因、臨床特點(diǎn)及預(yù)后,提高對(duì)該病的評(píng)估、干預(yù)及健康管理的水平。方法回顧性分析2013年10月-2014年9月廣州市婦女兒童醫(yī)療中心兒科急診40例輕度胃腸炎并良性嬰幼兒驚厥患兒的臨床資料及隨訪情況。結(jié)果 67.5%病例為12~23個(gè)月齡的兒童,以冬春季多見,47.5%患兒于病程第2天發(fā)生驚厥,絕大部分(97.5%)為全面發(fā)作,接近一半病例(47.5%)僅發(fā)作1次,發(fā)作持續(xù)時(shí)間為1~5 min。所有患者均無(wú)陽(yáng)性家族史,其中2例既往有熱性驚厥史。在所有患者中,輪狀病毒陽(yáng)性18例(45.0%)。全部患者腦脊液常規(guī)和生化均正常,其中2例腦電圖和頭顱磁共振同時(shí)異常。全部患者隨訪18個(gè)月,其中2例于1年內(nèi)出現(xiàn)熱性驚厥,1例出現(xiàn)反復(fù)無(wú)熱驚厥,最后確診為癲癇,需服用抗癲癇藥物。結(jié)論輕度胃腸炎并良性嬰幼兒驚厥常見于1~2歲兒童,多發(fā)生在冬春季胃腸炎的早期,輪狀病毒感染可增加其發(fā)生的風(fēng)險(xiǎn)。大部分預(yù)后良好,少數(shù)患兒有發(fā)展為癲癇的可能,對(duì)于驚厥發(fā)作次數(shù)多、持續(xù)時(shí)間長(zhǎng)和(或)腦電圖、影像學(xué)檢查異常者,需加強(qiáng)隨訪。
[Abstract]:Objective to investigate the etiology, clinical characteristics and prognosis of mild gastroenteritis with benign convulsion, and to improve the evaluation, intervention and health management of the disease. Methods the clinical data and follow-up data of 40 children with mild gastroenteritis and benign infantile convulsion in pediatric emergency department of Guangzhou Women and Children Medical Center from October 2013 to September 2014 were analyzed retrospectively. Results 67.5% of the cases were children aged 12 to 23 months, most of them were in winter and spring, 47.5% of them had convulsions on the second day of the disease course, most of them (97.5%) had full-scale seizures, and nearly half of the cases (47.5%) had only one attack. Duration of attack was 1: 5 min. All the patients had no positive family history, 2 of them had a history of febrile convulsion. Of all the patients, 18 (45.0%) were rotavirus positive. All patients had normal cerebrospinal fluid routine and biochemistry, 2 of them had abnormal EEG and cranial magnetic resonance simultaneously. All patients were followed-up for 18 months, 2 of them had febrile convulsion within one year, and 1 had recurrent non-febrile convulsion. Finally, epilepsy was diagnosed and antiepileptic drugs should be taken. Conclusion mild gastroenteritis with benign infantile convulsion is common in 1 or 2 year old children, and most of them occur in the early stage of gastroenteritis in winter and spring. Rotavirus infection may increase the risk of gastroenteritis. Most of the patients had good prognosis and a few children had the possibility of developing into epilepsy. For those with more seizures, longer duration and / or abnormal EEG and imaging examination, the follow-up should be strengthened.
【作者單位】： 廣東省廣州市婦女兒童醫(yī)療中心;
【分類號(hào)】：R725.7

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