過(guò)敏性哮喘患兒呼出氣一氧化氮變化及與血清過(guò)敏原特異性IgE的相關(guān)性
[Abstract]:Objective to observe the changes of nitric oxide (FeNO) in exhaled air of children with allergic asthma, and to explore the correlation between (FeNO) and serum allergen specific immunoglobulin (E (s Ig E). Methods from January 2014 to January 2006, 56 children with acute allergic asthma and 56 children with non-allergic asthma were selected as observation group and control group respectively. Detection of FeNO. in two groups by FeNO Analyzer The detection range of serum s Ig E, by Western blot was 20 allergens including dust mites, milk and egg proteins. The correlation between FeNO and serum s Ig E expression in observation group was analyzed. Results the FeNO of the observation group and the control group was (23.18 鹵3.82), (5.85 鹵1.19) ppb, compared with that of the control group (P 0.05). Total s Ig E was positive in 38 cases (67.85%) in the observation group and 5 cases (8.93%) in the control group. The serum total s Ig E levels in the observation group and the control group were (106.51 鹵8.26), (16.24 鹵2.31) IU/m / L, respectively. Compared with the P0.05.Spearman linear correlation analysis, the results of linear correlation analysis showed that there was a positive correlation between FeNO and total serum s Ig E in the observation group (r = 0.742P 0.05). Conclusion FeNO in children with allergic asthma is higher than that in children with non-allergic asthma. There was a positive correlation between the expression of FeNO and serum s Ig E in children with allergic asthma.
【作者單位】: 首都醫(yī)科大學(xué)附屬北京朝陽(yáng)醫(yī)院;
【分類(lèi)號(hào)】:R725.6
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