【摘要】：正重癥聯(lián)合免疫缺陷病(severe combined immunodeficiency,SCID)是一組細(xì)胞免疫缺陷、同時(shí)累及體液免疫的原發(fā)性免疫缺陷病(primary immunodeficiency,PID),根據(jù)有無(wú)B淋巴細(xì)胞,可將SCID分為T-B+及T-B-兩大類~([1])。隨著近期對(duì)SCID研究的逐步深入,根據(jù)患者外周血T淋巴細(xì)胞的絕對(duì)計(jì)數(shù)、T淋巴細(xì)胞增殖分化功能及致病基因的類型,將SCID劃分為3大類:經(jīng)典的SCID、泄漏型SCID(leaky
[Abstract]:Positive severe combined immunodeficiency disease (severe combined immunodeficiency,SCID) is a group of primary immunodeficiency disease (primary immunodeficiency,PID), which involves both cellular and humoral immunity. According to the presence of B lymphocytes, SCID can be divided into two categories: T-B and T-B-. With the recent progress in the study of SCID, according to the absolute count of T lymphocytes in peripheral blood of patients, the proliferation and differentiation function of T lymphocytes and the types of pathogenic genes, SCID is divided into three categories: classic SCID, leakage type SCID (leaky.
【作者單位】： 復(fù)旦大學(xué)附屬兒科醫(yī)院;
【分類號(hào)】：R722.1

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