【摘要】：目的探討和分析重癥肺炎患兒病原菌分布特點(diǎn)及抗菌藥物耐藥趨勢(shì)。方法選擇2014年1月-2016年12月期間醫(yī)院收治的218例重癥肺炎患兒作為臨床研究對(duì)象,并分別對(duì)重癥肺炎患兒的病原菌分布特點(diǎn)及抗菌藥物耐藥趨勢(shì)進(jìn)行統(tǒng)計(jì)分析。結(jié)果 218例重癥肺炎患兒中共檢出病原菌281株,以革蘭陰性菌為主,共147株占52.31%;以痰液檢出為主,共208株占74.02%;主要革蘭陰性菌對(duì)阿米卡星、亞胺培南、頭孢哌酮/舒巴坦、美羅培南均表現(xiàn)出較高的耐藥性,耐藥率均80.00%,對(duì)頭孢唑林和頭孢噻肟則均表現(xiàn)出較低的耐藥性,耐藥率均25.00%。結(jié)論重癥肺炎患兒病原菌分布以革蘭陰性菌為主,治療過(guò)程中應(yīng)根據(jù)病原菌的分布特點(diǎn)及耐藥趨勢(shì)科學(xué)合理選擇抗菌藥物。
[Abstract]:Objective to investigate and analyze the distribution of pathogenic bacteria and antimicrobial resistance in children with severe pneumonia. Methods 218 children with severe pneumonia from January 2014 to December 2016 were selected as clinical study objects. The distribution characteristics of pathogenic bacteria and the trend of antimicrobial drug resistance in children with severe pneumonia were analyzed statistically. Results 281 strains of pathogenic bacteria were detected in 218 children with severe pneumonia, 147 were Gram-negative bacteria (52.31), 208 were sputum (74.02%), and the main gram-negative bacteria were amikacin, imipenem, cefoperazone / sulbactam. Both meropenem and cefotaxime showed high drug resistance and resistance rates of 80.00g and 25.00g, respectively, and the resistance to cefazolin and cefotaxime were lower than those of cefazolin and cefotaxime. Conclusion Gram-negative bacteria are the main pathogens in children with severe pneumonia. In the course of treatment, antibiotics should be selected scientifically and reasonably according to the distribution characteristics of pathogenic bacteria and drug resistance trend.
【作者單位】： 溫州醫(yī)科大學(xué)附屬第二醫(yī)院兒童內(nèi)分泌科;
【分類號(hào)】：R725.6

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