辨證使用中成藥治療小兒急性上呼吸道感染的療效評(píng)價(jià)研究
本文選題:小兒感冒 + 文獻(xiàn)研究 ; 參考:《南京中醫(yī)藥大學(xué)》2012年碩士論文
【摘要】:本論文主要分理論研究與臨床研究兩部分。 理論研究 通過對(duì)中醫(yī)古代及現(xiàn)代醫(yī)學(xué)文獻(xiàn)的系統(tǒng)研究,探討兒童感冒(急性上呼吸道感染)的發(fā)生、發(fā)展、變化規(guī)律,總結(jié)治療小兒感冒的有效方藥,為更好地指導(dǎo)臨床,合理運(yùn)用中醫(yī)中藥治療本病提供科學(xué)的依據(jù)。 臨床研究 目的:觀察感冒治療前后的癥狀及體征積分變化,評(píng)價(jià)方案中試驗(yàn)藥物治療小兒感冒的有效性和安全性。初步探討病原學(xué)與證型間的相關(guān)性。 方法:按照隨機(jī)、平行對(duì)照的臨床試驗(yàn)方法,將170例符合診斷標(biāo)準(zhǔn)的感冒患兒,分為中藥組85例和西藥組85例,并對(duì)其辨證分型,分別服中成藥及抗病毒西藥。 結(jié)果:①臨床療效:試驗(yàn)組臨床痊愈占39.02%,顯效占45.12%,愈顯率為84.14%;對(duì)照組臨床痊愈率為25.61%,顯效率為42.68%,愈顯率為68.28%。兩組愈顯率比較,試驗(yàn)組優(yōu)于對(duì)照組(84.14%68.28%);②癥狀改善方面,治療后癥候積分及在流涕、納呆、大便等癥狀改善方面(P0.05),說明中藥組療效優(yōu)于西藥組;③體溫恢復(fù)正常時(shí)間方面,差異無統(tǒng)計(jì)學(xué)意(P0.05),提示中藥組、西藥組在體溫恢復(fù)正常時(shí)間療效相當(dāng);④病毒檢測率較高(57.76%)。 結(jié)論:中成藥治療小兒感冒療效確切,能改善眾多臨床癥狀;無明顯不良反應(yīng);患兒依從性高,適合推廣普及,應(yīng)用前景良好。
[Abstract]:This thesis is divided into two parts: theoretical research and clinical research. Through the systematic study of the ancient and modern medical literature of TCM, the occurrence, development and change of children's colds (acute upper respiratory tract infection) were discussed, and the effective prescriptions for the treatment of children's colds were summarized. In order to better guide clinical, rational use of traditional Chinese medicine to provide scientific basis for the treatment of this disease. Objective: to observe the changes of symptom and sign scores before and after treatment of colds and to evaluate the efficacy and safety of experimental drugs in the treatment of infantile colds. To explore the correlation between etiology and syndromes. Methods: according to the clinical trial method of random and parallel control, 170 children with colds who met the diagnostic criteria were divided into Chinese medicine group (85 cases) and western medicine group (85 cases). Results: the clinical curative effect of the trial group was 39.02%, the remarkable effect was 45.12%, the recovery rate was 84.14, the clinical cure rate of the control group was 25.61%, the effective rate was 42.68, and the effective rate was 68.28%. Compared with the two groups, the experimental group was superior to the control group (84.14h.28%) in improving the symptoms, the symptom score after treatment and the improvement of symptoms such as runny, anodyne and stool (P0.05), which indicated that the curative effect of the traditional Chinese medicine group was better than that of the western medicine group (84.14h.28%), and the recovery time of body temperature in the Chinese medicine group was better than that in the western medicine group. The difference was not statistically significant (P0.05), suggesting that the traditional Chinese medicine group, Western medicine group in the body temperature recovery time equivalent to the detection rate of virus 4 (57.76%). Conclusion: Chinese patent medicine is effective in treating infantile colds, it can improve many clinical symptoms, there is no obvious adverse reaction, the compliance of children is high, it is suitable for popularizing, and the application prospect is good.
【學(xué)位授予單位】:南京中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】:碩士
【學(xué)位授予年份】:2012
【分類號(hào)】:R272
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