兒童燒傷膿毒癥的高危因素分析
本文選題:小兒燒傷 + 膿毒癥; 參考:《寧夏醫(yī)科大學(xué)》2017年碩士論文
【摘要】:目的探討兒童燒傷膿毒癥發(fā)生的相關(guān)危險(xiǎn)因素,為預(yù)防兒童燒傷膿毒癥提供理論依據(jù)及臨床指導(dǎo)。方法通過(guò)回顧性分析2010年1月1日-2015年12月31日間在寧夏醫(yī)科大學(xué)總醫(yī)院住院治療的0-12歲燒傷合并膿毒癥120例及無(wú)膿毒癥2030例患兒病歷資料,分為病例組及對(duì)照組,觀察性別、年齡、燒傷面積、燒傷深度、燒傷程度、燒傷后是否及時(shí)復(fù)蘇、燒傷后是否及時(shí)清創(chuàng)、燒傷后入院時(shí)間、是否合并吸入性損傷、是否合并其他部位感染、是否合并休克及燒傷類型等相關(guān)變量及其與患兒發(fā)生膿毒癥的相關(guān)性,將有統(tǒng)計(jì)學(xué)意義的指標(biāo)納入非條件Logistic回歸分析,篩查出與兒童燒傷并發(fā)膿毒癥相關(guān)的危險(xiǎn)因素。結(jié)果本研究收集病例總數(shù)為2150例,其中膿毒癥患兒有120例,發(fā)生率5.58%。多因素分析顯示:合并吸入性損傷(OR=5.793),有延遲復(fù)蘇(OR=4.703)、合并休克(OR=3.904)、合并其余部位感染(OR=3.386)、重度燒傷(OR=3.028)、燒傷面積25%(OR=1.658)、年齡越小(OR=1.402)、未及時(shí)入院(OR=1.004)是燒傷患兒并發(fā)膿毒癥的危險(xiǎn)因素,而淺度燒傷(OR=0.760)和及時(shí)清創(chuàng)(OR=0.031)是保護(hù)因素。結(jié)論1.兒童燒傷后發(fā)生膿毒癥是多個(gè)因素共同作用的結(jié)果,各因素之間可以相互影響,互相作用。2.臨床上應(yīng)加強(qiáng)對(duì)兒童燒傷膿毒癥高危因素的重視,并采取有效措施降低膿毒癥的患病率。
[Abstract]:Objective to explore the risk factors of burn sepsis in children and to provide theoretical basis and clinical guidance for the prevention of burn sepsis in children. Methods the medical records of 120 burn patients with sepsis aged 0-12 and 2030 children without sepsis who were hospitalized in General Hospital of Ningxia Medical University from January 1, 2010 to December 31, 2015 were retrospectively analyzed. The patients were divided into two groups: case group and control group. Age, area, depth, degree of burn, resuscitation after burn, debridement after burn, admission time after burn, inhalation injury, infection in other parts, In order to screen out the risk factors associated with sepsis in children with burn and other related variables such as shock and burn type and their correlation with sepsis the statistically significant indexes were included in the non-conditional logistic regression analysis in order to screen out the risk factors associated with sepsis in children. Results 2150 cases were collected in this study, of which 120 cases were sepsis, the incidence was 5.58%. Multivariate analysis showed that complicated inhalation injury (OR5.793), delayed resuscitation (OR4.703), shock (OR3.904), infection of other sites (OR3.386), severe burn (OR3.028), burn area of 25% (OR1.658), younger age (OR1.402), delayed hospitalization (OR1.004) were the risk factors of sepsis in burn children. Shallow burn (ORO 0.760) and timely debridement (ORO 0.031) were protective factors. Conclusion 1. Sepsis after burns in children is the result of multiple factors, which can interact with each other. 2. 2. In clinic, we should pay more attention to the high risk factors of burn sepsis in children, and take effective measures to reduce the prevalence rate of sepsis.
【學(xué)位授予單位】:寧夏醫(yī)科大學(xué)
【學(xué)位級(jí)別】:碩士
【學(xué)位授予年份】:2017
【分類號(hào)】:R726.5
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