本文選題：危重患兒 + 容量負(fù)荷��； 參考：《臨床兒科雜志》2017年07期

【摘要】：目的探討容量超負(fù)荷(FO)與危重患兒急性腎損傷(AKI)、病死率的相關(guān)性,及FO對(duì)死亡的預(yù)測(cè)價(jià)值。方法選取入住兒童重癥監(jiān)護(hù)病房(PICU)的危重癥患兒為研究對(duì)象進(jìn)行前瞻性研究。評(píng)估其病程中FO水平,并于入院24小時(shí)內(nèi)進(jìn)行PRISMⅢ評(píng)分。以二元logistic回歸評(píng)估在校正混雜因素后FO與AKI及病死率的關(guān)系,采用受試者工作特征曲線下面積(AUC)評(píng)估FO對(duì)死亡的預(yù)測(cè)價(jià)值。結(jié)果共納入362例患兒,平均FO≥5%26例(7.18%),發(fā)生AKI 24例(6.63%),死亡18例(5.0%)。危重患兒入住PICU 7天內(nèi),平均FO(OR=1.26,95%CI:1.10~1.43,P=0.001)和最大FO(OR=1.12,95%CI:1.02~1.23,P=0.018)均與AKI顯著相關(guān);然而在校正年齡和PRISMⅢ后,二者與AKI無(wú)相關(guān)(P0.05)。在校正AKI和疾病嚴(yán)重程度等潛在的混雜因素后,平均FO與病死率仍顯著相關(guān)(AOR=1.34,95%CI:1.12~1.60,P=0.002)。平均FO預(yù)測(cè)死亡風(fēng)險(xiǎn)的AUC為0.801(P0.001)。結(jié)論容量超負(fù)荷與危重患兒的AKI和預(yù)后相關(guān),并對(duì)危重患兒的死亡有重要的預(yù)測(cè)價(jià)值。
[Abstract]:Objective to investigate the correlation between volume overload FOO and acute renal injury (AK) mortality in critically ill children, and the predictive value of FO to death. Methods A prospective study was carried out on critically ill children admitted to the Children's intensive Care Unit (ICU). The level of FO in the course of disease was evaluated and PRISM 鈪，

本文編號(hào)：1978434