發(fā)布時間：2018-05-31 02:33

  本文選題：食管狹窄 + 氣囊擴(kuò)張術(shù)　； 參考：《中國內(nèi)鏡雜志》2017年08期

【摘要】：目的比較球囊擴(kuò)張術(shù)(EBD)治療小兒食道狹窄及賁門失弛緩的療效,分析預(yù)后影響因素。方法 2012年1月-2014年12月共28例患兒納入研究。其中,食道狹窄22例,賁門失弛緩6例,利用擴(kuò)張球囊進(jìn)行治療。結(jié)果 28例患兒共接受57次球囊擴(kuò)張術(shù),隨訪12~36個月,28例全部成功。其中,23例患兒癥狀完全緩解(82.14%),4例患兒部分緩解(14.28%),1例無效(3.57%),1例復(fù)發(fā)(3.57%)。治療成功率、有效率、并發(fā)癥發(fā)生率及復(fù)發(fā)率兩組患兒比較差異無統(tǒng)計(jì)學(xué)意義。食道狹窄患兒中,多個狹窄患兒并發(fā)癥較單個狹窄患兒多,狹窄直徑越小并發(fā)癥越多,比較差異有統(tǒng)計(jì)學(xué)意義(P0.05);治療效果與狹窄直徑和狹窄個數(shù)顯著相關(guān)(P0.05)。賁門失弛緩組患兒中,發(fā)病年齡及明確診斷前癥狀持續(xù)的時間均對EBD治療效果沒有顯著影響。結(jié)論 EBD是小兒食道狹窄及賁門失弛緩安全有效的治療手段;狹窄直徑和狹窄個數(shù)是影響食道狹窄治療效果最重要的因素,而第一次球囊擴(kuò)張與食道閉鎖手術(shù)之間的時間則是術(shù)后食道狹窄患兒最重要的影響因素。
[Abstract]:Objective to compare the efficacy and prognostic factors of balloon dilatation (EBD) in the treatment of esophageal stenosis and achalasia in children. Methods from January 2012 to December 2014, 28 children were included in the study. 22 cases of esophageal stenosis and 6 cases of achalasia were treated with dilated balloon. Results there were 57 times of balloon dilatation in 28 cases, and 28 cases were successfully followed up for 12 ~ 36 months. Among them, 23 cases had complete remission (82.14%), 4 cases had partial remission (14.28%), 1 case had no effect (3.57%) and 1 case had recurrence (3.57%). There was no significant difference in treatment success rate, effective rate, complication rate and recurrence rate between the two groups. In the patients with esophageal stenosis, there were more complications in multiple stenosis children than in single stenosis children, and the smaller the stenosis diameter was, the more complications were. The difference was statistically significant (P 0.05), and the therapeutic effect was significantly correlated with the stenosis diameter and the number of stenosis. In the achalasia group, the age of onset and the duration of definite pre-diagnosis symptoms had no significant effect on the treatment effect of EBD. Conclusion EBD is a safe and effective method for the treatment of esophageal stenosis and achalasia in children and the diameter and number of stenosis are the most important factors affecting the therapeutic effect of esophageal stenosis. The time between the first balloon dilation and esophageal atresia was the most important factor.
【作者單位】： 廣東省深圳市兒童醫(yī)院消化內(nèi)科;
【分類號】：R725.7

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