本文選題：新生兒呼吸窘迫綜合征 + 經(jīng)鼻無創(chuàng)高頻振蕩通氣��； 參考：《廣東醫(yī)學(xué)》2017年13期

【摘要】：目的探討患有重度新生兒呼吸窘迫綜合征(NRDS)的早產(chǎn)兒撤機(jī)后使用經(jīng)鼻無創(chuàng)高頻振蕩通氣(NHFOV)和經(jīng)鼻持續(xù)氣道正壓通氣(NCPAP)的效果,以確定NHFOV是否可提高撤機(jī)成功率。方法選擇入住新生兒重癥監(jiān)護(hù)病房、胎齡28~35周、需要有創(chuàng)呼吸支持并且在生后3周內(nèi)撤機(jī)的重度NRDS早產(chǎn)兒,共入選65例,撤機(jī)后隨機(jī)分為NHFOV組(34例)和NCPAP組(31例),若應(yīng)用這兩種方式不能維持則需再次氣管插管機(jī)械通氣。主要觀察指標(biāo)為撤機(jī)成功率、失敗原因分析以及使用無創(chuàng)呼吸支持后1、12、24、48、72 h血?dú)庵醒醴謮?PaO_2)、二氧化碳分壓(PaCO_2)、PaO_2/氧濃度(FiO_2)。結(jié)果 NHFOV組撤機(jī)成功率為85.29%,高于NCPAP組的61.29%(P0.05)。兩組總用氧時(shí)間、氣胸、支氣管肺發(fā)育不良、壞死性小腸結(jié)腸炎和顱內(nèi)出血發(fā)生率(Ⅲ度及以上)差異無統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論對(duì)于撤機(jī)后的早產(chǎn)兒,使用NHFOV比NCPAP有更高的成功率。
[Abstract]:Objective to investigate the effect of NHFOV in the treatment of premature infants with severe neonatal respiratory distress syndrome (NRDS) by using noninvasive high frequency oscillatory ventilation (NHFOV) and continuous positive airway pressure ventilation (CPAP) after weaning, so as to determine whether NHFOV can improve the success rate of weaning. Methods 65 cases of severe NRDS premature infants who were admitted to neonatal intensive care unit (NICU) and whose gestational age was 28 ~ 35 weeks and needed invasive respiratory support and were weaned within 3 weeks after birth were selected. After weaning, the patients were randomly divided into NHFOV group (n = 34) and NCPAP group (n = 31). The main outcome measures were success rate of weaning, cause analysis of failure, and PaO2 partial pressure in blood gas (Pao _ 2 / Pao _ 2 / O _ 2 / O _ 2 / O _ 2 / P _ 2O _ 2 / P _ 2O _ 2) after non-invasive respiratory support for 1 h, Pao _ 2 and PaCO _ 2 / P _ O _ 2 / P _ O _ 2 / P _ 2O _ 2 / P _ 2O _ 2 / P _ 2O _ 2. Results the success rate of weaning in NHFOV group was 85.29%, higher than that in NCPAP group (61.29%). There was no significant difference in total oxygen use time, pneumothorax, bronchopulmonary dysplasia, necrotizing enterocolitis and intracranial hemorrhage (鈪，

本文編號(hào)：1870052